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Studies from M. Schade and Colleagues Provide New Data on Colloids and Interface Science (Lipophilic nucleic acids--a flexible construction kit for...

July 15, 2014



Studies from M. Schade and Colleagues Provide New Data on Colloids and Interface Science (Lipophilic nucleic acids--a flexible construction kit for organization and functionalization of surfaces)

By a News Reporter-Staff News Editor at Journal of Technology -- Researchers detail new data in Colloids and Interface Science. According to news originating from Berlin, Germany, by VerticalNews correspondents, research stated, "Lipophilic nucleic acids have become a versatile tool for structuring and functionalization of lipid bilayers and biological membranes as well as cargo vehicles to transport and deliver bioactive compounds, like interference RNA, into cells by taking advantage of reversible hybridization with complementary strands. This contribution reviews the different types of conjugates of lipophilic nucleic acids, and their physicochemical and self-assembly properties."

Our news journalists obtained a quote from the research, "Strategies for choosing a nucleic acid, lipophilic modification, and linker are discussed. Interaction with lipid membranes and its stability, dynamic structure and assembly of lipophilic nucleic acids upon embedding into biological membranes are specific points of the review."

According to the news editors, the research concluded: "A large diversity of conjugates including lipophilic peptide nucleic acid and siRNA provides tailored solutions for specific applications in bio-and nanotechnology as well as in cell biology and medicine, as illustrated through some selected examples."

For more information on this research see: Lipophilic nucleic acids--a flexible construction kit for organization and functionalization of surfaces. Advances In Colloid and Interface Science, 2014;208():235-51. (Elsevier - www.elsevier.com; Advances In Colloid and Interface Science - www.elsevier.com/wps/product/cws_home/500842)

The news correspondents report that additional information may be obtained from M. Schade, Humboldt-Universitat zu Berlin, Institut fur Biologie, Invalidenstr 42, 10115 Berlin, Germany. Additional authors for this research include D. Berti, D. Huster, A. Herrmann and A. Arbuzova.

Keywords for this news article include: Berlin, Europe, Germany, Colloids and Interface Science.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Journal of Technology


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