Researchers' Work from Athlone Institute of Technology Focuses on Essential Amino Acids [Preparation and characterization of poly(ethylene glycol)-block-poly[epsilon-(benzyloxycarbonyl)-L-lysine] thin films for biomedical applications]
By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Essential Amino Acids. According to news reporting originating from Athlone, Ireland, by NewsRx correspondents, research stated, "The nanoscale architectures evident in the thin films of self-assembling hybrid block copolymers-which are tailored to inherit the advantageous properties of their constituent synthetic (homo)polymer and polypeptide blocks-have continued to inspire a variety of new applications in different fields, including biomedicine. The thin films of symmetric hybrid block copolymer, alpha-methoxy-poly(ethylene glycol)-block-poly[epsilon-(benzyloxycarbonyl)-l-lysine], MPEG(112)-b-PLL(Z)(17), were prepared by solvent casting in five different solvents and characterized using Attenuated Total Reflectance-Fourier Transform Infrared spectroscopy, Thermogravimetric analysis, Derivative Thermogravimetric analysis, Differential Scanning Calorimetry, Contact Angle goniometry, Wide-Angle X-ray Diffraction, and Scanning Electron Microscopy."
Our news editors obtained a quote from the research from the Athlone Institute of Technology, "Film thickness was estimated to be 51 +/- A 23 mu m by the 'step-height' method, using a thickness gauge. Although no significant change to the block copolymer's microstructure was observed, its solvent-cast films displayed divergent physical and thermal properties. The resulting cast films proved more thermally stable than the bulk but indicated greater block miscibility. Additionally, the thin films of MPEG(112)-b-PLL(Z)(17) preserved the microphase separation exhibited by the bulk copolymer albeit with appreciable loss of crystallinity. The surface properties of the polymer-air interface were diverse as were the effects of the casting solvents."
According to the news editors, the research concluded: "Oriented equilibrium morphologies are also evident in some of the as-cast thin films."
For more information on this research see: Preparation and characterization of poly(ethylene glycol)-block-poly[epsilon-(benzyloxycarbonyl)-L-lysine] thin films for biomedical applications. Polymer Bulletin, 2014;71(7):1691-1709. Polymer Bulletin can be contacted at: Springer, 233 Spring St, New York, NY 10013, USA. (Springer - www.springer.com; Polymer Bulletin - www.springerlink.com/content/0170-0839/)
The news editors report that additional information may be obtained by contacting J.U. Izunobi, Athlone Inst Technol, Mat Res Inst, Athlone, Ireland. Additional authors for this research include L.M. Geever and C.L. Higginbotham (see also Essential Amino Acids).
Keywords for this news article include: Europe, Lysine, Athlone, Ireland, Alkenes, Ethylene Glycols, Basic Amino Acids, Diamino Amino Acids, Essential Amino Acids
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC