Researchers from University Putra Malaysia Provide Details of New Studies and Findings in the Area of Connective Tissue Cells (Osteoblasts growth behaviour on bio-based calcium carbonate aragonite nanocrystal)
Our news journalists obtained a quote from the research from University Putra Malaysia, "Cell viability and proliferation were assessed by MTT and BrdU assays, and LDH was measured to determine the effect of CaCO3 nanocrystals on cell membrane integrity. Cellular morphology was examined by SEM and fluorescence microscopy. The results showed that CaCO3 nanocrystals had no toxic effects to some extent. Cell proliferation, alkaline phosphatase activity, and protein synthesis were enhanced by the nanocrystals when compared to the control. Cellular interactions were improved, as indicated by SEM and fluorescent microscopy. The production of VEGF and TGF-1 was also affected by the CaCO3 nanocrystals."
According to the news editors, the research concluded: "Therefore, bio-based CaCO3 nanocrystals were shown to stimulate osteoblast differentiation and improve the osteointegration process."
For more information on this research see: Osteoblasts growth behaviour on bio-based calcium carbonate aragonite nanocrystal.
The news correspondents report that additional information may be obtained from A. Shafiu Kamba,
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