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Researchers from University Putra Malaysia Provide Details of New Studies and Findings in the Area of Connective Tissue Cells (Osteoblasts growth...

July 18, 2014



Researchers from University Putra Malaysia Provide Details of New Studies and Findings in the Area of Connective Tissue Cells (Osteoblasts growth behaviour on bio-based calcium carbonate aragonite nanocrystal)

By a News Reporter-Staff News Editor at Health & Medicine Week -- Researchers detail new data in Connective Tissue Cells. According to news originating from Selangor, Malaysia, by NewsRx correspondents, research stated, "Calcium carbonate (CaCO3) nanocrystals derived from cockle shells emerge to present a good concert in bone tissue engineering because of their potential to mimic the composition, structure, and properties of native bone. The aim of this study was to evaluate the biological response of CaCO3 nanocrystals on hFOB 1.19 and MC3T3 E-1 osteoblast cells in vitro."

Our news journalists obtained a quote from the research from University Putra Malaysia, "Cell viability and proliferation were assessed by MTT and BrdU assays, and LDH was measured to determine the effect of CaCO3 nanocrystals on cell membrane integrity. Cellular morphology was examined by SEM and fluorescence microscopy. The results showed that CaCO3 nanocrystals had no toxic effects to some extent. Cell proliferation, alkaline phosphatase activity, and protein synthesis were enhanced by the nanocrystals when compared to the control. Cellular interactions were improved, as indicated by SEM and fluorescent microscopy. The production of VEGF and TGF-1 was also affected by the CaCO3 nanocrystals."

According to the news editors, the research concluded: "Therefore, bio-based CaCO3 nanocrystals were shown to stimulate osteoblast differentiation and improve the osteointegration process."

For more information on this research see: Osteoblasts growth behaviour on bio-based calcium carbonate aragonite nanocrystal. Biomed Research International, 2014;2014():215097 (see also Connective Tissue Cells).

The news correspondents report that additional information may be obtained from A. Shafiu Kamba, Laboratory of Molecular Biomedicine, Institute of Bioscience, Universiti Putra Malaysia (UPM), 43400 Serdang, Selangor, Malaysia.

Keywords for this news article include: Asia, Anions, Selangor, Malaysia, Alkalies, Minerals, Osteoblasts, Bone Research, Carbonic Acid, Calcium Carbonate, Calcium Compounds, Connective Tissue Cells.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Health & Medicine Week


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