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Researchers from Sri Ramachandra University Describe Findings in Nanoparticles (Spectroscopic investigations, antimicrobial, and cytotoxic activity...

July 15, 2014



Researchers from Sri Ramachandra University Describe Findings in Nanoparticles (Spectroscopic investigations, antimicrobial, and cytotoxic activity of green synthesized gold nanoparticles)

By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Nanoparticles have been published. According to news originating from Tamil Nadu, India, by NewsRx correspondents, research stated, "The gold nanoparticles (AuNPs) were synthesized by using naturally available Punica Granatum fruit extract as reducing and stabilizing agent. The biosynthesized AuNPs was characterized by using UV-Vis, fluorescence, high resolution transmission electron microscopy (HRTEM), X-ray diffraction (XRD), Fourier transform infrared (FTIR) and thermogravimetric (TGA) analysis."

Our news journalists obtained a quote from the research from Sri Ramachandra University, "The surface plasmon resonance (SPR) band at 585 nm confirmed the reduction of auric chloride to AuNPs. The crystalline nature of the biosynthesized AuNPs was confirmed from the HRTEM images, XRD and selected area electron diffraction (SAED) pattern. The HRTEM images showed the mixture of triangular and spherical-like AuNPs having size between 5 and 20 nm. The weight loss of the AuNPs was measured by TGA as a function of temperature under a controlled atmosphere. The biomolecules are responsible for the reduction of AuCl4- ions and the formation of stable AuNPs which was confirmed by FTIR measurement. The synthesized AuNPs showed an excellent antibacterial activity against Candida albicans (ATCC 90028), Aspergillus flavus (ATCC 10124), Staphylococcus aureus (ATCC 25175), Salmonella typhi (ATCC 14028) and Vibrio cholerae (ATCC 14033). The minimum inhibitory concentration (MIC) of AuNPs was recorded against various microorganisms."

According to the news editors, the research concluded: "Further, the synthesized AuNPs shows an excellent cytotoxic result against HeLa cancer cell lines at different concentrations."

For more information on this research see: Spectroscopic investigations, antimicrobial, and cytotoxic activity of green synthesized gold nanoparticles. Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy, 2014;129():484-490. Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy can be contacted at: Pergamon-Elsevier Science Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, England (see also Nanoparticles).

The news correspondents report that additional information may be obtained from S. Lokina, Sri Ramachandra Univ, Madras 600116, Tamil Nadu, India. Additional authors for this research include R. Suresh, K. Giribabu, A. Stephen, R.L. Sundaram and V. Narayanan.

Keywords for this news article include: Asia, India, Tamil Nadu, Nanotechnology, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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