Researchers from Institute of Optoelectronics Report Recent Findings in Optical Coherence Tomography (Detection of breast surgical margins with optical coherence tomography imaging: a concept evaluation study)
By a News Reporter-Staff News Editor at Biotech Week -- Data detailed on Optical Coherence Tomography have been presented. According to news reporting from Magurele, Romania, by NewsRx journalists, research stated, "This study aimed to evaluate the concept of using high-resolution optical coherence tomography (OCT) imaging to rapidly assess surgical specimens and determine if cancer positive margins were left behind in the surgical bed. A mouse model of breast cancer was used in this study."
The news correspondents obtained a quote from the research from the Institute of Optoelectronics, "Surgical specimens from 30 animals were investigated with OCT and automated interpretation of the OCT images was performed and tested against histopathology findings. Specimens from 10 animals were used to build a training set of OCT images, while the remaining 20 specimens were used for a validation set of images. The validation study showed that automated interpretation of OCT images can differentiate tissue types and detect cancer positive margins with at least 81% sensitivity and 89% specificity. The findings of this pilot study suggest that OCT imaging of surgical specimens and automated interpretation of OCT data may enable in the future real-time feedback to the surgeon about margin status in patients with breast cancer, and potentially with other types of cancers. Currently, such feedback is not provided and if positive margins are left behind, patients have to undergo another surgical procedure."
According to the news reporters, the research concluded: "Therefore, this approach can have a potentially high impact on breast surgery outcome."
For more information on this research see: Detection of breast surgical margins with optical coherence tomography imaging: a concept evaluation study. Journal of Biomedical Optics, 2014;19(5):056001 (see also Optical Coherence Tomography).
Our news journalists report that additional information may be obtained by contacting D. Savastru, National Institute of Optoelectronics, 409 Atomistilor Street, Magurele, Ilfov, RO-077125, Romania. Additional authors for this research include E.W. Chang, S. Miclos, M.B. Pitman, A. Patel and N. Iftimia.
Keywords for this news article include: Europe, Cancer, Romania, Magurele, Oncology, Imaging Technology, Optical Coherence Tomography.
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC