Researchers at Division of Cardiology Target Angiology (Impact of cardiac computed tomography of the interatrial septum before pulmonary vein isolation)
By a News Reporter-Staff News Editor at Cardiovascular Week -- New research on Angiology is the subject of a report. According to news originating from Luzern, Switzerland, by NewsRx correspondents, research stated, "Multidetector computed tomography (MDCT) may be useful to identify patients with patent foramen ovale (PFO). The aim of this study was to analyze whether a MDCT performed before pulmonary vein isolation reliably detects a PFO that may be used for access to the left atrium."
Our news journalists obtained a quote from the research from the Division of Cardiology, "In 79 consecutive patients, who were referred for catheter ablation of symptomatic paroxysmal or persistent atrial fibrillation (AF), the presence of a PFO was explored by MDCT and transesophageal echocardiography (TEE). TEE was considered as the gold standard, and quality of TEE was good in all patients. In 16 patients (20.3%), MDCT could not be used for analysis because of artifacts, mainly because of AF. On TEE, a PFO was found in 15 (23.8%) of the 63 patients with usable MDCT. MDCT detected six PFO of which four were present on TEE. This corresponded to a sensitivity of 26.7%, a specificity of 95.8%, a negative predictive value of 80.7%, and a positive predictive value of 66.7%. The receiver operating characteristics curve of MDCT for the detection of PFO was 0.613 (95% confidence interval 0.493-0.732). MDCT may detect a PFO before pulmonary isolation. However, presence of AF may lead to artifacts on MDCT impeding a meaningful analysis."
According to the news editors, the research concluded: "Furthermore, in this study sensitivity and positive predictive value of MDCT were low and therefore MDCT was not a reliable screening tool for detection of PFO."
For more information on this research see: Impact of cardiac computed tomography of the interatrial septum before pulmonary vein isolation. Pacing and Clinical Electrophysiology, 2013;36(10):1245-50. (Wiley-Blackwell - www.wiley.com/; Pacing and Clinical Electrophysiology - onlinelibrary.wiley.com/journal/10.1111/(ISSN)1540-8159)
The news correspondents report that additional information may be obtained from R. Kobza, Division of Cardiology, Luzerner Kantonsspital, Luzern, Switzerland. Additional authors for this research include A.W. Schoenenberger, F. Cuculi, M. Zuber, C. Auf Der Maur, R. Buhmann, T.J. Resink and P. Erne (see also Angiology).
Keywords for this news article include: Luzern, Europe, Angiology, Cardiology, Switzerland, Pulmonary Veins, Imaging Technology, Atrial Fibrillation, Computed Tomography.
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