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Reports Outline Drug Delivery Systems Study Findings from University of Illinois (Understanding nano-bio interactions to improve nanocarriers for...

July 16, 2014

Reports Outline Drug Delivery Systems Study Findings from University of Illinois (Understanding nano-bio interactions to improve nanocarriers for drug delivery)

By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Drugs and Therapies. According to news reporting from Chicago, Illinois, by NewsRx journalists, research stated, "The ability of cancer-targeted nanoparticles (NPs) to reach their site of action and evoke a desired biological response after intravenous injection is critical to achieve clinically significant in vivo efficacy. Throughout their journey in the body, NPs must successfully traverse biological environments such as blood circulation and tumor microenvironments."

The news correspondents obtained a quote from the research from the University of Illinois, "The interactions that occur at the interface between NPs and biological components are complex, requiring a thorough understanding of the 'nano-bio' interactions to design NPs with maximal therapeutic indices. In this article, we review the challenges presented by the multiscale, important biocompartments that NPs face, describe the crucial nano-bio interactions present at each stage, and discuss potential strategies to overcome those challenges."

According to the news reporters, the research concluded: "This review suggests design considerations for NPs to optimally modulate their physicochemical properties to achieve desired biological responses, which are expected to aid chemists, engineers, and clinical scientists to design and develop highly effective delivery platforms for cancer therapy."

For more information on this research see: Understanding nano-bio interactions to improve nanocarriers for drug delivery. MRS Bulletin, 2014;39(3):227-237. MRS Bulletin can be contacted at: Cambridge Univ Press, 32 Avenue Of The Americas, New York, NY 10013-2473, USA. (Cambridge University Press -; MRS Bulletin -

Our news journalists report that additional information may be obtained by contacting R.M. Pearson, University of Illinois, Chicago, IL 60607, United States. Additional authors for this research include H.J. Hsu, J. Bugno and S. Hong (see also Drugs and Therapies).

Keywords for this news article include: Chicago, Illinois, United States, Drugs and Therapies, Drug Delivery Systems, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Biotech Week

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