Recent Findings from University of Cairo Provides New Insights into Oligopeptides (Photoluminescence and photostability investigations of biocompatible semiconductor nanocrystals coated with glutathione using low laser power)
By a News Reporter-Staff News Editor at Life Science Weekly -- Researchers detail new data in Peptides. According to news originating from Cairo, Egypt, by NewsRx correspondents, research stated, "Great efforts are currently devoted to fabricate high-quality quantum dots (QDs) in aqueous solutions for biomedical applications. Two biocompatible systems consisting of core (CdSe) and core/shell (CdSe/ZnS) QDs surface modified with glutathione (GSH), named CdSe-GSH and CdSe/ZnS-GSH, respectively, were built."
Our news journalists obtained a quote from the research from the University of Cairo, "Upon photoirradiation using low laser power, both systems in HEPES buffer (pH 7.2) showed significant photoluminescence (PL) enhancements. CdSe/ZnS-GSH showed much less blue shifts in excitonic absorption and emission peaks without photobleaching compared with CdSe-GSH QDs system. X-ray diffraction showed that there is no change in the crystalline phase structure of the CdSe/ZnS-GSH QDs system after 1 h irradiation. Cell viability assessment, in the dark, demonstrated that no cytotoxic effects were shown upon incubation CdSe/ZnS-GSH QDs with normal human skin cell line for periods up to 72 h and at concentrations up to 100 nM."
According to the news editors, the research concluded: "The present study demonstrates that CdSe/ZnS-GSH QDs system exhibits a high photostability with a relatively high PL efficiency in aqueous medium following low intensity photoexcitation, without dark cytotoxicity, making this system attractive for several important biomedical applications."
For more information on this research see: Photoluminescence and photostability investigations of biocompatible semiconductor nanocrystals coated with glutathione using low laser power. Journal of Nanoparticle Research, 2014;16(6):1-13. Journal of Nanoparticle Research can be contacted at: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands. (Springer - www.springer.com; Journal of Nanoparticle Research - www.springerlink.com/content/1388-0764/)
The news correspondents report that additional information may be obtained from S.A. Ibrahim, Cairo University, Natl Canc Inst, Cairo 11796, Egypt. Additional authors for this research include W. Ahmed and T. Youssef (see also Peptides).
Keywords for this news article include: Cairo, Egypt, Africa, Electronics, Glutathione, Nanocrystal, Oligopeptides, Semiconductor, Nanotechnology, Emerging Technologies
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