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New Findings on Skin Cancer from Linkoping University Summarized (Photodynamic effects of zinc oxide nanowires in skin cancer and fibroblast)

July 15, 2014



By a News Reporter-Staff News Editor at Cancer Weekly -- New research on Oncology is the subject of a report. According to news originating from Norrkoping, Sweden, by NewsRx correspondents, research stated, "Cytotoxic effects of zinc oxide (ZnO) nanomaterials, individual and conjugated with a photosensitizer (protoporphyrin IX), were studied in the presence and absence of ultraviolet light exposure (240 nm of light wavelength for a very short time exposure) in cell cultures of human normal and cancerous skin models."

Our news journalists obtained a quote from the research from Linkoping University, "Zinc Oxide nanowires (ZnO NWs) were grown on the capillary tip and conjugated with protoporphyrin IX (PpIX). This coated tip was used as tool/pointer for intracellular drug delivery protocol in suggested normal as well as carcinogenic cellular models."

According to the news editors, the research concluded: "After true delivery of optimal drug, the labelled biological model was irradiated with UV-A, which led to a loss of mitochondrial membrane potential, as tested by neutral red assay (NRA)."

For more information on this research see: Photodynamic effects of zinc oxide nanowires in skin cancer and fibroblast. Lasers in Medical Science, 2014;29(3):1189-1194. Lasers in Medical Science can be contacted at: Springer London Ltd, 236 Grays Inn Rd, 6TH Floor, London WC1X 8HL, England. (Springer - www.springer.com; Lasers in Medical Science - www.springerlink.com/content/0268-8921/)

The news correspondents report that additional information may be obtained from M. Fakhar-e-Alam, Linkoping University, Dept. of Sci & Technol, S-60174 Norrkoping, Sweden. Additional authors for this research include S. Kishwar and M. Willander (see also Oncology).

Keywords for this news article include: Biotechnology, Sweden, Europe, Oncology, Chemicals, Chemistry, Norrkoping, Zinc Oxide, Fibroblasts, Skin Cancer, Photodynamics, Skin Neoplasms, Zinc Compounds, Protoporphyrins, Connective Tissue Cells

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Cancer Weekly


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