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New Findings on Nanotechnology from University of California Summarized (Functionalized ultrasound-propelled magnetically guided nanomotors: toward...

July 16, 2014



New Findings on Nanotechnology from University of California Summarized (Functionalized ultrasound-propelled magnetically guided nanomotors: toward practical biomedical applications)

By a News Reporter-Staff News Editor at Biotech Week -- A new study on Nanotechnology is now available. According to news originating from La Jolla, California, by NewsRx correspondents, research stated, "Magnetically guided ultrasound-powered nanowire motors, functionalized with bioreceptors and a drug-loaded polymeric segment, are described for 'capture and transport' and drug-delivery processes. These high-performance fuel-free motors display advanced capabilities and functionalities, including magnetic guidance, coordinated aligned movement, cargo towing, capture and isolation of biological targets, drug delivery, and operation in real-life biological and environmental media."

Our news journalists obtained a quote from the research from the University of California, "The template-prepared three-segment Au-Ni-Au nanowire motors are propelled acoustically by mechanical waves produced by a piezoelectric transducer. An embedded nickel segment facilitates a magnetically guided motion as well as transport of large 'cargo' along predetermined trajectories. Substantial improvement in the speed and power is realized by the controlled concavity formation at the end of the motor nanowire using a sphere lithography protocol. Functionalization of the Au segments with lectin and antiprotein A antibody bioreceptors allows capture and transport of E. coli and S. aureus bacteria, respectively. Potential therapeutic applications are illustrated in connection to the addition of a pH-sensitive drug-loaded polymeric (PPy-PSS) segment."

According to the news editors, the research concluded: "The attractive capabilities of these fuel-free acoustically driven functionalized Au-Ni-Au nanowires, along with the simple preparation procedure and minimal adverse effects of ultrasonic waves, make them highly attractive for diverse in vivo biomedical applications."

For more information on this research see: Functionalized ultrasound-propelled magnetically guided nanomotors: toward practical biomedical applications. Acs Nano, 2013;7(10):9232-40. (American Chemical Society - www.acs.org; Acs Nano - www.pubs.acs.org/journal/ancac3)

The news correspondents report that additional information may be obtained from V. Garcia-Gradilla, Dept. of Nanoengineering, University of California, San Diego , La Jolla, California 92093, United States. Additional authors for this research include J. Orozco, S. Sattayasamitsathit, F. Soto, F. Kuralay, A. Pourazary, A. Katzenberg, W. Gao, Y. Shen and J. Wang (see also Nanotechnology).

Keywords for this news article include: La Jolla, California, United States, Nanotechnology, North and Central America.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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