News Column

New Findings from National Cancer Institute Describe Advances in Cancer Gene Therapy (IL-2: The First Effective Immunotherapy for Human Cancer)

July 14, 2014

By a News Reporter-Staff News Editor at Cancer Gene Therapy Week -- Research findings on Biotechnology are discussed in a new report. According to news reporting originating in Bethesda, Maryland, by NewsRx editors, the research stated, "The ability of IL-2 to expand T cells with maintenance of functional activity has been translated into the first reproducible effective human cancer immunotherapies."

The news reporters obtained a quote from the research from National Cancer Institute, "The administration of IL-2 can lead to durable, complete, and apparently curative regressions in patients with metastatic melanoma and renal cancer. The growth of large numbers of tumor-infiltrating lymphocytes with in vitro anti-cancer activity in IL-2 has led to the development of cell transfer therapies that are highly effective in patients with melanoma."

According to the news reporters, the research concluded: "The genetic modification of T cells with genes encoding alpha beta TCRs or chimeric Ag receptors and the administration of these cells after expansion in IL-2 have extended effective cell transfer therapy to other cancer types."

For more information on this research see: IL-2: The First Effective Immunotherapy for Human Cancer. Journal of Immunology, 2014;192(12):5451-5458. Journal of Immunology can be contacted at: Amer Assoc Immunologists, 9650 Rockville Pike, Bethesda, MD 20814, USA. (The American Association of Immunologists -; Journal of Immunology -

Our news correspondents report that additional information may be obtained by contacting S.A. Rosenberg, National Cancer Institute, Surg Branch, Bethesda, MD 20892, United States (see also Biotechnology).

Keywords for this news article include: Biotechnology, Bethesda, Maryland, Genetics, Oncology, United States, Immunotherapy, Immunomodulation, Cancer Gene Therapy, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Cancer Gene Therapy Week

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