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New Biotechnology Data Have Been Reported by Researchers at Southeast University (Synthesis of a near-infrared fluorescent probe and its application...

July 16, 2014



New Biotechnology Data Have Been Reported by Researchers at Southeast University (Synthesis of a near-infrared fluorescent probe and its application in imaging of MCF-7 cells)

By a News Reporter-Staff News Editor at Biotech Week -- Investigators discuss new findings in Technology. According to news reporting originating from Nanjing, People's Republic of China, by NewsRx correspondents, research stated, "IR-789, a novel near-infrared fluorescent probe, was designed, synthesized, and applied to living cells. The probe exhibited better response fluorescence characteristics than the only FDA-approved agent, indocyanine green."

Our news editors obtained a quote from the research from Southeast University, "Cell experiments showed that the probe had high affinity and without apparent cytotoxicity. Fluorescent image experiments in living MCF-7 cells (human breast adenocarcinoma cell line) further demonstrated the potential applications of the probe in biological systems. The probe effectively prevented the influence of autofluorescence and native cellular species in biological systems."

According to the news editors, the research concluded: "It also exhibited high sensitivity, good photostability, and excellent cell membrane permeability."

For more information on this research see: Synthesis of a near-infrared fluorescent probe and its application in imaging of MCF-7 cells. Biotechnology Letters, 2014;36(6):1203-7. Biotechnology Letters can be contacted at: Springer, 233 Spring Street, New York, NY 10013, USA. (Springer - www.springer.com; Biotechnology Letters - www.springerlink.com/content/0141-5492/)

The news editors report that additional information may be obtained by contacting C. Sun, School of Chemistry & Chemical Engineering, Southeast University, Nanjing, 210096, People's Republic of China. Additional authors for this research include Y. Wu, J. Cai, P. Wang, X. Zong, G. Zhou, L. Li and M. Ji (see also Technology).

Publisher contact information for the journal Biotechnology Letters is: Springer, 233 Spring Street, New York, NY 10013, USA.

Keywords for this news article include: Asia, Nanjing, Technology, People's Republic of China.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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