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Investigators at University Erlangen-Nurnberg Describe Findings in Tissue Engineering [Fabrication of electrospun poly (3-hydroxybutyrate)/poly...

July 16, 2014

Investigators at University Erlangen-Nurnberg Describe Findings in Tissue Engineering [Fabrication of electrospun poly (3-hydroxybutyrate)/poly (epsilon-caprolactone)/silica hybrid fibermats with and without calcium addition]

By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Biomedicine and Biomedical Engineering. According to news reporting out of Erlangen, Germany, by NewsRx editors, research stated, "Poly (3-hydroxybutyrate)(PHB)/poly (epsilon-caprolactone)(PCL)/silica hybrid scaffolds with and without calcium were fabricated through the combination of electrospinning and sal-gel methods. In this paper, the effects of different amounts of silica Sol on the morphology, mechanical and thermal properties of hybrid scaffolds were studied."

Our news journalists obtained a quote from the research from University Erlangen-Nurnberg, "The results indicated that as the silica content increased to 50 wt%, the ultimate tensile strength and modulus were enhanced to 191% and 614%, respectively. In addition, the presence of silica decreased the elongation at break significantly. Calcium addition changed the morphology of the hybrid scaffolds from relatively dense fibermats to highly fluffy porous structures, which may be due to the ionization of Ca2+ in the polymer solution. Chemical interactions between the different components and the thermal properties were also based on FTIR, DSC and TGA measurements. The addition of inorganic components significantly decreased the crystallinity of PHB and PCL, which was also confirmed by XRD analysis."

According to the news editors, the research concluded: "Due to the intrinsic performance of the biopolymer and inorganic components, the scaffolds in the present study have great potential for tissue engineering applications."

For more information on this research see: Fabrication of electrospun poly (3-hydroxybutyrate)/poly (epsilon-caprolactone)/silica hybrid fibermats with and without calcium addition. European Polymer Journal, 2014;55():222-234. European Polymer Journal can be contacted at: Pergamon-Elsevier Science Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, England. (Elsevier -; European Polymer Journal -

Our news journalists report that additional information may be obtained by contacting Y.P. Ding, University of Erlangen Nurnberg, Dept. of Mat Sci & Engn, Inst Biomat, D-91058 Erlangen, Germany. Additional authors for this research include J.A. Roether, A.R. Boccaccini and D.W. Schubert (see also Biomedicine and Biomedical Engineering).

Keywords for this news article include: Tissue Engineering, Biomedicine and Biomedical Engineering, Europe, Germany, Erlangen, Bioengineering, Carboxylic Acids, Hydroxybutyrates, Organic Chemicals, 3-Hydroxybutyric Acid

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Source: Biotech Week

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