Investigators at Max-Planck-Institute of Colloids and Interfaces Target Colloids and Interface Science (Langmuir monolayers as models to study processes at membrane surfaces)
Our news editors obtained a quote from the research from the Max-Planck-Institute of Colloids and Interfaces, "Monolayers are convenient quasi-two-dimensional model systems. This review focuses on interactions between amphiphilic molecules in binary and ternary mixtures as well as on interfacial interactions with interesting biomolecules dissolved in the subphase. The phase state of monolayers can be easily triggered at constant temperature by increasing the packing density of the lipids by compression. Simultaneously the monolayer structure changes are followed in situ by grazing incidence X-ray diffraction or IRRAS. The interactions can be indirectly determined by the observed structure changes. Additionally, the yield of enzymatic reaction can be quantitatively determined, secondary structures of peptides and proteins can be measured and compared with those observed in bulk. In this way, the influence of a confinement on the structural properties of biomolecules can be determined. The adsorption of DNA can be quantified as well as the competing adsorption of ions at charged interfaces. The influence of modified nanoparticles on model membranes can be clearly determined."
According to the news editors, the research concluded: "In this review, the relevance and utility of Langmuir monolayers as suitable models to study physical and chemical interactions at membrane surfaces are clearly demonstrated."
For more information on this research see: Langmuir monolayers as models to study processes at membrane surfaces. Advances In Colloid and Interface Science, 2014;208():197-213. (
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