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Findings on Biological Pigments Reported by Investigators at University of Wyoming (Supramolecular ssDNA Templated Porphyrin and Metalloporphyrin...

July 15, 2014

Findings on Biological Pigments Reported by Investigators at University of Wyoming (Supramolecular ssDNA Templated Porphyrin and Metalloporphyrin Nanoassemblies with Tunable Helicity)

By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Biological Factors have been published. According to news reporting out of Laramie, Wyoming, by NewsRx editors, research stated, "Free-base and nickel porphyrin-diaminopurine conjugates were formed by hydrogen-bond directed assembly on single-stranded oligothymidine templates of different lengths into helical multiporphyrin nanoassemblies with highly modular structural and chiroptical properties. Large red-shifts of the Soret band in the UV/Vis spectroscopy confirmed strong electronic coupling among assembled porphyrin-diaminopurine units."

Our news journalists obtained a quote from the research from the University of Wyoming, "Slow annealing rates yielded preferentially right-handed nanostructures, whereas fast annealing yielded left-handed nanostructures. Time-dependent DFT simulations of UV/Vis and CD spectra for model porphyrin clusters templated on the canonical B-DNA and its enantio-meric form, were employed to confirm the origin of observed chiroptical properties and to assign the helicity of porphyrin nanoassemblies. Molar CD and CD anisotropy g factors of dialyzed templated porphyrin nanoassemblies showed very high chiroptical anisotropy. The DNA-templated porphyrin nanoassemblies displayed high thermal and pH stability. The structure and handedness of all assemblies was preserved at temperatures up to + 85 degrees C and pH between 3 and 12."

According to the news editors, the research concluded: "High-resolution transition electron microscopy confirmed formation of DNA-templated nickel(II) porphyrin nanoassemblies and their self-assembly into helical fibrils with micrometer lengths."

For more information on this research see: Supramolecular ssDNA Templated Porphyrin and Metalloporphyrin Nanoassemblies with Tunable Helicity. Chemistry-A European Journal, 2014;20(7):1878-1892. Chemistry-A European Journal can be contacted at: Wiley-V C H Verlag Gmbh, Boschstrasse 12, D-69469 Weinheim, Germany (see also Biological Factors).

Our news journalists report that additional information may be obtained by contacting G. Sargsyan, University of Wyoming, Dept. of Chem, Laramie, WY 82071, United States. Additional authors for this research include B.M. Leonard, J. Kubelka and M. Balaz.

Keywords for this news article include: Laramie, Wyoming, United States, Nanostructural, Nanostructures, Nanotechnology, Supramolecular, Metalloporphyrins, Biological Factors, Biological Pigments, Emerging Technologies, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Life Science Weekly

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