News Column

Findings in Gene Therapy Reported from University of Michigan (Smelling the roses and seeing the light: gene therapy for ciliopathies)

July 17, 2014

By a News Reporter-Staff News Editor at Gene Therapy Weekly -- Current study results on Biotechnology have been published. According to news originating from Ann Arbor, Michigan, by NewsRx correspondents, research stated, "Alterations in cilia formation or function underlie a growing class of pleiotropic disorders termed ciliopathies. The genetic basis of ciliopathies is remarkably complex, with an incomplete but expanding list of more than 89 loci implicated in various disorders."

Our news journalists obtained a quote from the research from the University of Michigan, "Current treatment of ciliopathies is limited to symptomatic therapy. However, our growing understanding of ciliopathy genetics, coupled with recent advances in gene delivery and endogenous gene and transcript repair demonstrated thus far in tissues of the eye, nose, and airway, offers hope for curative measures in the near future."

According to the news editors, the research concluded: "This review highlights these advances, as well as the challenges that remain with the development of personalized medicine for treating a very complex spectrum of disease, penetrant in a variety of organ systems."

For more information on this research see: Smelling the roses and seeing the light: gene therapy for ciliopathies. Trends In Biotechnology, 2013;31(6):355-63. (Elsevier -; Trends In Biotechnology -

The news correspondents report that additional information may be obtained from J.C. McIntyre, Dept. of Pharmacology, University of Michigan, Ann Arbor, MI, United States. Additional authors for this research include C.L. Williams and J.R Martens (see also Biotechnology).

Keywords for this news article include: Biotechnology, Michigan, Ann Arbor, Gene Therapy, United States, Bioengineering, North and Central America.

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Source: Gene Therapy Weekly

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