News Column

Findings from Harvard School of Medicine in Neuroscience Reported (Clinical features of brain metastasis from salivary gland tumors)

July 16, 2014



By a News Reporter-Staff News Editor at Biotech Week -- A new study on Nervous System Research is now available. According to news reporting originating in Boston, Massachusetts, by NewsRx journalists, research stated, "Salivary gland tumors comprise a group of 24 tumor subtypes with a wide range of clinical behaviors and propensities for metastasis. Several prognostic factors have been identified that help predict the development of systemic metastases, most commonly to the lung, liver, or bone."

The news reporters obtained a quote from the research from the Harvard School of Medicine, "Metastases to the brain are rare. To better understand the behavior of salivary gland tumors that metastasise to the brain, we performed a retrospective cohort analysis on a series of patients to highlight features of their medical and surgical management. From 2007 to 2011, a database of 4117 elective craniotomies were queried at a single institution to identify patients surgically treated for salivary gland metastases to the brain. Three patients were identified. Histologic subtypes included salivary duct carcinoma, poorly differentiated carcinoma, and papillary mucinous adenocarcinoma. They had all undergone previous treatment for their primary malignancy. The mean time to intracranial metastasis was 48 months from initial diagnosis (range, 14-91 months). Treatment for intracranial metastases included surgical resection, whole brain radiation, stereotactic radiosurgery, and chemotherapy."

According to the news reporters, the research concluded: "Intracranial metastases from salivary gland tumors are rare, present years after diagnosis of the primary tumor, and are treatable with multimodality therapy."

For more information on this research see: Clinical features of brain metastasis from salivary gland tumors. Journal of Clinical Neuroscience, 2013;20(11):1533-7. (Elsevier - www.elsevier.com; Journal of Clinical Neuroscience - www.elsevier.com/wps/product/cws_home/623056)

Our news correspondents report that additional information may be obtained by contacting A.S. Venteicher, Dept. of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, White Building Room 502, Boston, MA 02114, United States. Additional authors for this research include B.P. Walcott, S.A. Sheth, M. Snuderl, A.P. Patel, W.T. Curry and B.V Nahed (see also Nervous System Research).

Keywords for this news article include: Boston, Massachusetts, United States, Nervous System Research, North and Central America.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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