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Data on Tissue Engineering Discussed by Researchers at Delft University of Technology (Fabrication of Metallic Biomedical Scaffolds with the Space...

July 16, 2014



Data on Tissue Engineering Discussed by Researchers at Delft University of Technology (Fabrication of Metallic Biomedical Scaffolds with the Space Holder Method: A Review)

By a News Reporter-Staff News Editor at Biotech Week -- A new study on Biomedicine and Biomedical Engineering is now available. According to news originating from Delft, Netherlands, by NewsRx correspondents, research stated, "Bone tissue engineering has been increasingly studied as an alternative approach to bone defect reconstruction. In this approach, new bone cells are stimulated to grow and heal the defect with the aid of a scaffold that serves as a medium for bone cell formation and growth."

Our news journalists obtained a quote from the research from the Delft University of Technology, "Scaffolds made of metallic materials have preferably been chosen for bone tissue engineering applications where load-bearing capacities are required, considering the superior mechanical properties possessed by this type of materials to those of polymeric and ceramic materials. The space holder method has been recognized as one of the viable methods for the fabrication of metallic biomedical scaffolds. In this method, temporary powder particles, namely space holder, are devised as a pore former for scaffolds. In general, the whole scaffold fabrication process with the space holder method can be divided into four main steps: (i) mixing of metal matrix powder and space-holding particles; (ii) compaction of granular materials; (iii) removal of space-holding particles; (iv) sintering of porous scaffold preform. In this review, detailed procedures in each of these steps are presented. Technical challenges encountered during scaffold fabrication with this specific method are addressed."

According to the news editors, the research concluded: "Strategies are yet to be developed to address problematic issues raised, such as powder segregation, pore inhomogeneity, distortion of pore sizes and shape, uncontrolled shrinkage and contamination."

For more information on this research see: Fabrication of Metallic Biomedical Scaffolds with the Space Holder Method: A Review. Materials, 2014;7(5):3588-3622. Materials can be contacted at: Mdpi Ag, Postfach, Ch-4005 Basel, Switzerland. (Wiley-Blackwell - www.wiley.com/; Materials - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1521-4176)

The news correspondents report that additional information may be obtained from B. Arifvianto, Delft University of Technology, Fac Mech Maritime & Mat Engn, Biomat Technol Sect, Dept. of Biomech Engn, NL-2628 CD Delft, Netherlands (see also Biomedicine and Biomedical Engineering).

Keywords for this news article include: Biomedicine and Biomedical Engineering, Delft, Europe, Netherlands, Bone Research, Bioengineering, Bone Regeneration, Bone-Tissue Engineering

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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