"Having worked in the field of tumor immunology and on the development of the first tumor vaccine to be approved by a regulatory body (Melacine), I am fascinated by novel approaches to cancer immunotherapy," Dr. Minev said. "The approach being developed by Batu Biologics is completely unique in that this is the first time the blood vessels that feed the tumor are being used as a target of immunotherapy. This provides a completely different approach to cancer therapy since: a) blood vessels do not mutate like tumors mutate, thus reducing chances of the cells becoming resistant to therapy; b) for every single blood vessel cell that is killed, approximately 200-300 tumor cells die, thus higher potential for efficacy exists; and c) tumor blood vessels are in direct contact with the immune system via the blood. In contrast, tumor cells are very difficult to completely eradicate due to areas inside the tumor that lack sufficient circulation and are impenetrable by immune system cells."
The ValloVaxTM product is based on blood vessel cells generated in the laboratory in a manner which makes them resemble tumor blood vessels. The immune response against the "artificial tumor blood vessels" is believed to result in the selective killing of tumor blood vessels.
"Leveraging the translational oncology experience of Dr. Minev, especially his work in the area of peptide vaccines and nanotechnology, will not only accelerate the
Earlier this month, Batu Biologics announced efforts to raise
With the recent successes of immunotherapy in a variety of tumors, Batu Biologics believes there is an increasing unmet need for non-toxic immune modulators that can augment efficacy of existing therapeutics. Our team is motivated to bring novel therapeutics to the forefront of medical research that use the power of the body's own immune system to extend life expectancy. Batu Biologics has filed two provisional patents in the field of cancer immunotherapy and plans to significantly expand its IP in 2014. Corporate Address:9255 Towne Centre DriveSuite 450San Diego, CA 92121 Laboratory Address:
Keywords for this news article include: Oncology, Immunology, Vaccination, Immunization, Legal Issues, Immunotherapy, Batu Biologics, Cancer Vaccines, Immunomodulation,
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC
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