Reports from University of Surrey Highlight Recent Findings in Supercritical Fluids (Application of nano-particle coatings to carrier particles using an integrated fluidized bed supercritical fluid precipitation process)
By a News Reporter-Staff News Editor at Journal of Technology -- Investigators publish new report on Supercritical Fluids. According to news reporting out of Guildford, United Kingdom, by VerticalNews editors, research stated, "Production of active ingredients such as pharmaceuticals in nano-particulate form is highly desirable but the resulting product is difficult to handle and to use in applications. A novel process is described for coating nanoparticles onto excipient particles of c. 300 mu m by rapid expansion of a supercritical solution (RESS) into two types of modified proprietary equipment: a Wurster coater and a fluidized bed."
Our news journalists obtained a quote from the research from the University of Surrey, "This novel approach has been demonstrated through the successful deposition of six mimics for active ingredients (benzoic acid, adamantane, ferrocene, phenanthrene, stearic acid and vitamin K3) on carrier excipient particles of microcrystalline cellulose (MCC). Evidence from SEM, EDX and Confocal Raman microscopy suggests that the coating particles are below 30 nm in size. Unlike most conventional coating processes, this approach avoids the use of liquids and high temperatures."
According to the news editors, the research concluded: "As a wide range of actives and excipients can potentially be employed, the approach is applicable across the process and product industries, in particular pharmaceutical, household goods, personal care and catalyst industries."
For more information on this research see: Application of nano-particle coatings to carrier particles using an integrated fluidized bed supercritical fluid precipitation process. Journal of Supercritical Fluids, 2014;91():7-14. Journal of Supercritical Fluids can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Journal of Supercritical Fluids - www.elsevier.com/wps/product/cws_home/600250)
Our news journalists report that additional information may be obtained by contacting G.A. Leeke, University of Surrey, Dept. of Chem & Proc Engn, Guildford GU2 7XH, Surrey, United Kingdom. Additional authors for this research include T.J. Lu, R.H. Bridson and J.P.K. Seville.
Keywords for this news article include: Europe, Guildford, United Kingdom, Supercritical Fluids
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