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Investigators at Martin-Luther-University Have Reported New Data on Science (Lateral surface engineering of hybrid lipid-BCP vesicles and selective...

August 6, 2014



Investigators at Martin-Luther-University Have Reported New Data on Science (Lateral surface engineering of hybrid lipid-BCP vesicles and selective nanoparticle embedding)

By a News Reporter-Staff News Editor at Journal of Engineering -- Data detailed on Science have been presented. According to news reporting originating in Halle Saale, Germany, by VerticalNews journalists, research stated, "Bio-inspired recognition between macromolecules and antibodies can be used to reveal the location of amphiphilic block copolymers (BCPs) in model biomembranes and their subsequent scaffolding with nanoparticles (NPs). Potential applications of this novel class of lipid-BCP membranes require an understanding of their compositional heterogeneities with a variety of different molecules including natural proteins or synthetic NPs, whose selective incorporation into a specific part of phase separated membranes can serve as a model system for the targeted delivery of therapeutics."

The news reporters obtained a quote from the research from Martin-Luther-University, "We demonstrate the selective incorporation of polymer-functionalized CdSe NPs into the polymer-rich domains in vesicular hybrid membranes using 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC, Tm=41 C) or 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC, Tm=-20 C) as the lipid component. Furthermore, we demonstrate a method to detect PIB-PEO based amphiphilic BCPs on liposomal surfaces by a PEO binding antibody (anti-PEO)."

According to the news reporters, the research concluded: "As a result, hybrid membrane morphologies, which depend on the lipid/BCP composition, are selectively monitored and engineered."

For more information on this research see: Lateral surface engineering of hybrid lipid-BCP vesicles and selective nanoparticle embedding. Soft Matter, 2014;10(6):831-9. (Royal Society of Chemistry - www.rsc.org/; Soft Matter - pubs.rsc.org/en/journals/journalissues/sm)

Our news correspondents report that additional information may be obtained by contacting M. Schulz, Martin-Luther University Halle-Wittenberg, Chair of Macromolecular Chemistry, Faculty of Natural Sciences II (Chemistry, Physics and Mathematics), Institute of Chemistry, D-06120 Halle (Saale), Germany. Additional authors for this research include A. Olubummo, K. Bacia and W.H Binder.

Keywords for this news article include: Europe, Germany, Science, Halle Saale, Engineering.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Journal of Engineering


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