Study Results from Qufu Normal University in the Area of Excitatory Amino Acids Reported (Redox potentials of dopamine and its supramolecular complex with aspartic acid)
By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Excitatory Amino Acids. According to news reporting originating in Shandong, People's Republic of China, by NewsRx journalists, research stated, "Dopamine (DA) can be oxidized to dopamine quinone (DAquinone) through a one-step, two-electron redox reaction. The electron transfer property of DA and its supramolecular complex with aspartic acid (Asp) has been investigated by the theoretical calculations."
The news reporters obtained a quote from the research from Qufu Normal University, "We calculated the standard redox potentials (E (o)) of DA/DAquinone at the MP2/6-31G(d,p)//B3LYP/6-31G(d,p), MP2/6-31+G(d,p)//B3LYP/6-31+G(d,p), MP2/6-31G(d,p)//B3LYP/6-311G(d,p), and MP2/6-311+G(d,p)//B3LYP/6-311+G(d,p) levels. Comparing the experimental value, the redox potentials of DA/DAquinone obtained at MP2//B3LYP/6-311G(d,p) and MP2//B3LYP/6-311+G(d,p) levels can be considered as the upper and lower estimates. DA can form supramolecular complex (DA-Asp) with Asp through hydrogen bond (H-bond). Therefore, the values of 0.631 and 0.628 V obtained at MP2//B3LYP/6-311G(d,p) and MP2//B3LYP/6-311+G(d,p) levels for DA-Asp/DAquinone-Asp can be proposed as the upper and lower estimates of a probable (about 0.630 V) value of the corresponding redox potential."
According to the news reporters, the research concluded: "The calculated E (o) values of DA-Asp/DAquinone-Asp at the four theoretical levels are upper than those of DA/DAquinone, which indicates that the formation of H-bonds weaken the electron-donating ability of DA."
For more information on this research see: Redox potentials of dopamine and its supramolecular complex with aspartic acid. Russian Journal of Physical Chemistry A, 2014;88(7):1085-1090. Russian Journal of Physical Chemistry A can be contacted at: Maik Nauka, Interperiodica, Springer, 233 Spring St, New York, NY 10013-1578, USA. (Pleiades Publishing - www.maik.ru)
Our news correspondents report that additional information may be obtained by contacting T. Liu, Qufu Normal Univ, Sch Chem & Chem Engn, Qufu 273165, Shandong, People's Republic of China. Additional authors for this research include L.L. Han, C.M. Du and Z.Y. Yu (see also Excitatory Amino Acids).
Keywords for this news article include: Asia, Shandong, Aspartic Acid, Nanotechnology, Supramolecular, Acidic Amino Acids, Emerging Technologies, Excitatory Amino Acids, Dicarboxylic Amino Acids, People's Republic of China
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