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Researchers from University of Jinan Report on Findings in Breast Cancer (Ultrasensitive dual amplification sandwich immunosensor for breast cancer...

August 5, 2014



Researchers from University of Jinan Report on Findings in Breast Cancer (Ultrasensitive dual amplification sandwich immunosensor for breast cancer susceptibility gene based on sheet materials)

By a News Reporter-Staff News Editor at Cancer Weekly -- Investigators publish new report on Oncology. According to news originating from Jinan, People's Republic of China, by NewsRx correspondents, research stated, "A new electrochemical dual amplification sandwich immunosensor (DASI) was designed for ultrasensitive and accurate detection of the breast cancer susceptibility gene based on the combination of N-doped graphene, hydroxypropyl chitosan and Co3O4 mesoporous nanosheets. N-doped graphene has better electroconductibility than traditional graphene."

Our news journalists obtained a quote from the research from the University of Jinan, "It is an ideal electrochemical material with a large specific surface area and low resistance. Hydroxypropyl chitosan replaces the pure chitosan in immobilization of the sensor to achieve the sensitivity increase. Co3O4 mesoporous nanosheets can enhance the effective area of the immunoreaction. This kind of dual amplification sandwich immunosensor was first used for the detection of the breast cancer susceptibility gene. It has a wide linear response range of 0.001-35 ng mL(-1) and a minimum detection limit of 0.33 pg mL(-1). It was demonstrated that the stability, selectivity and reproducibility of the sensor were acceptable."

According to the news editors, the research concluded: "The fabricated immunosensor shows great potential applications in early disease diagnosis."

For more information on this research see: Ultrasensitive dual amplification sandwich immunosensor for breast cancer susceptibility gene based on sheet materials. Analyst, 2014;139(12):3061-8. (Royal Society of Chemistry - www.rsc.org/; Analyst - pubs.rsc.org/en/journals/journalissues/an)

The news correspondents report that additional information may be obtained from X. Ren, Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, People's Republic of China. Additional authors for this research include T. Yan, S. Zhang, X. Zhang, P. Gao, D. Wu, B. Du and Q. Wei (see also Oncology).

Keywords for this news article include: Asia, Jinan, Oncology, Chemistry, Nanosheets, Breast Cancer, Nanotechnology, Women's Health, Electrochemical, Emerging Technologies, People's Republic of China.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Cancer Weekly


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