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Research Conducted at Ben-Gurion University of the Negev Has Provided New Information about Peptides and Proteins (Electronic Properties of Amyloid...

August 5, 2014



Research Conducted at Ben-Gurion University of the Negev Has Provided New Information about Peptides and Proteins (Electronic Properties of Amyloid beta-Based Peptide Filaments with Different Non-Natural Heterocyclic Side Chains)

By a News Reporter-Staff News Editor at Life Science Weekly -- Research findings on Proteins are discussed in a new report. According to news reporting from Beer Sheva, Israel, by NewsRx journalists, research stated, "The incorporation of non-canonical amino acids with aromatic side chains is considered to be a promising way to improve and control the electronic properties of self-assembled peptide nanostructures. In this work, we have studied the influence of aromatic ring heteroatom on the electronic properties of amyloid beta-derived peptide fiber networks."

The news correspondents obtained a quote from the research from the Ben-Gurion University of the Negev, "We show that the incorporation of furan instead of thiophene side chains results in only small changes in the resistivity of the peptide network, with a threefold increase in the sheet resistance and a small decrease in the contact resistance. These changes can be explained by a twofold decrease in the diameter of the self-assembled fibers."

According to the news reporters, the research concluded: "These characteristics open the way to the use of furan-instead of thiophene-based analogues as non-natural side-chain modifications of peptides for electronic applications; this makes the fibrils more biodegradable and biorenewable."

For more information on this research see: Electronic Properties of Amyloid beta-Based Peptide Filaments with Different Non-Natural Heterocyclic Side Chains. Israel Journal of Chemistry, 2014;54(5-6):703-707. Israel Journal of Chemistry can be contacted at: Wiley-V C H Verlag Gmbh, Boschstrasse 12, D-69469 Weinheim, Germany. (Wiley-Blackwell - www.wiley.com/; Israel Journal of Chemistry - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1869-5868)

Our news journalists report that additional information may be obtained by contacting M. Amit, Ben Gurion University of the Negev, Ilse Katz Inst Nanoscale Sci & Technol, IL-84105 Beer Sheva, Israel (see also Proteins).

Keywords for this news article include: Asia, Israel, Amyloid, Proteins, Beer Sheva

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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