Reports Outline Materials Engineering Study Results from Mie University (Preparation of mesoporous silica thin films by photocalcination method and their adsorption abilities for various proteins)
By a News Reporter-Staff News Editor at Life Science Weekly -- Research findings on Materials Engineering are discussed in a new report. According to news originating from Mie, Japan, by NewsRx correspondents, research stated, "Mesoporous silica (MPS) thin film biosensor platforms were established. MPS thin films were prepared from tetraethoxysilane (TEOS) via using sol-gel and spin-coating methods using a poly-(ethylene oxide)-block-poly-(propylene oxide)-block-poly-(ethylene oxide) triblock polymer, such as P123 ((E)(20)(PO)(70)(EO)(20)) or F127 ((EO)(106)(PO)(70)(EO)(106)), as the structure-directing agent."
Our news journalists obtained a quote from the research from Mie University, "The MPS thin film prepared using P123 as the mesoporous template and treated via vacuum ultraviolet (VUV) irradiation to remove the triblock copolymer had a more uniform pore array than that of the corresponding film prepared via thermal treatment. Protein adsorption and enzyme-linked immunosorbent assay (ELISA) on the synthesized MPS thin films were also investigated. VUV-irradiated MPS thin films adsorbed a smaller quantity of protein A than the thermally treated films; however, the human immunoglobulin G (IgG) binding efficiency was higher on the former. In addition, protein A-IgG specific binding on MPS thin films was achieved without using a blocking reagent; i.e., nonspecific adsorption was inhibited by the uniform pore arrays of the films. Furthermore, VUV-irradiated MPS thin films exhibited high sensitivity for ELISA testing, and cytochrome c adsorbed on the MPS thin films exhibited high catalytic activity and recyclability."
According to the news editors, the research concluded: "These results suggest that MPS thin films are attractive platforms for the development of novel biosensors."
For more information on this research see: Preparation of mesoporous silica thin films by photocalcination method and their adsorption abilities for various proteins. Materials Science & Engineering C-Materials for Biological Applications, 2014;40():42-48. Materials Science & Engineering C-Materials for Biological Applications can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands (see also Materials Engineering).
The news correspondents report that additional information may be obtained from K. Kato, Mie Univ, Dept. of Chem Mat, Grad Sch Engn, Tsu, Mie 5148570, Japan. Additional authors for this research include H. Nakamura, Y. Yamauchi, K. Nakanishi and M. Tomita.
Keywords for this news article include: Mie, Asia, Japan, Materials Engineering
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