Reports from University of Washington Provide New Insights into Optical Coherence Tomography (Improved microcirculation imaging of human skin in vivo using optical microangiography with a correlation mapping mask)
By a News Reporter-Staff News Editor at Biotech Week -- A new study on Optical Coherence Tomography is now available. According to news reporting from Seattle, Washington, by NewsRx journalists, research stated, "Optical microangiography based on optical coherence tomography (OCT) is prone to noise that arises from a static tissue region. Here, we propose a method that can significantly reduce this noise."
The news correspondents obtained a quote from the research from the University of Washington, "The method is developed based on an approach that uses the magnitude information of OCT signals to produce tissue microangiograms, especially suitable for the case where a swept-source OCT system is deployed. By combined use of two existing OCT microangiography methods-ultrahigh-sensitive optical microangiography (UHS-OMAG) and correlation mapping OCT (cmOCT)-the final tissue microangiogram is generated by masking UHS-OMAG image using the binary representation of cmOCT image. We find that this process masks the residual static artifacts while preserving the vessel structures. The noise rejection capability of the masked approach (termed as mOMAG) is tested on a tissue-like flow phantom as well as an in vivo human skin tissue. Compared to UHS-OMAG and cmOCT, we demonstrate that the proposed method is capable of achieving improved signal-to-noise ratio in providing microcirculation images."
According to the news reporters, the research concluded: "Finally, we show its clinical potential by quantitatively assessing the vascular difference between a burn scar and a normal skin of human subject in vivo."
For more information on this research see: Improved microcirculation imaging of human skin in vivo using optical microangiography with a correlation mapping mask. Journal of Biomedical Optics, 2014;19(3):187-195. Journal of Biomedical Optics can be contacted at: Spie-Soc Photo-Optical Instrumentation Engineers, 1000 20TH St, PO Box 10, Bellingham, WA 98225, USA (see also Optical Coherence Tomography).
Our news journalists report that additional information may be obtained by contacting W.J. Choi, University of Washington, Dept. of Bioengn, Seattle, WA 98195, United States. Additional authors for this research include R. Reif, S. Yousefi and R.K.K. Wang.
Keywords for this news article include: Seattle, Washington, United States, North and Central America, Optical Coherence Tomography
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