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Report Summarizes Nanotechnology Study Findings from Henan University (Synthesis of silica nanospheres with Ni2+-iminodiacetic acid for protein...

August 5, 2014



Report Summarizes Nanotechnology Study Findings from Henan University (Synthesis of silica nanospheres with Ni2+-iminodiacetic acid for protein separation)

By a News Reporter-Staff News Editor at Life Science Weekly -- Data detailed on Nanotechnology have been presented. According to news reporting originating in Kaifeng, People's Republic of China, by NewsRx journalists, research stated, "Silica (SiO2) nanospheres (NSs) with immobilized metal ligands have been prepared for the affinity separation of proteins. First, SiO2 NSs were prepared by controlled hydrolysis of tetraethoxysilane in a basic aqueous-ethanol solution."

The news reporters obtained a quote from the research from Henan University, "Then through reaction of iminodiacetic acid (IDA) with 3-glycidoxypropyltrimethoxysilane and immobilization of them onto the surfaces of above SiO2 NSs, novel affinity adsorbents with IDA chelating groups were obtained. After chelating Ni2+ ions, the SiO2-IDA-Ni2+ NSs were applied to separate his-tagged proteins directly from the mixture of lysed cells."

According to the news reporters, the research concluded: "The SiO2-IDA-Ni2+ NSs present negligible nonspecific protein adsorption and high protein binding ability (28.3 mg/g)."

For more information on this research see: Synthesis of silica nanospheres with Ni2+-iminodiacetic acid for protein separation. Journal of Sol-Gel Science and Technology, 2014;71(2):380-384. Journal of Sol-Gel Science and Technology can be contacted at: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands. (Springer - www.springer.com; Journal of Sol-Gel Science and Technology - www.springerlink.com/content/0928-0707/)

Our news correspondents report that additional information may be obtained by contacting B.J. Li, Henan Univ, Dept. of Chem & Chem Engn, Kaifeng 475004, People's Republic of China. Additional authors for this research include Y.N. Zhang, L.Q. Cao, Y.H. Wu and Y.B. Zhao (see also Nanotechnology).

Keywords for this news article include: Asia, Kaifeng, Nanosphere, Nanotechnology, Emerging Technologies, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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