Recent Studies from Jilin University Add New Data to Chalcogens (Heterogeneous Assembled Nanocomplexes for Ratiometric Detection of Highly Reactive Oxygen Species in Vitro and in Vivo)
By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Chalcogens have been published. According to news reporting originating from Changchun, People's Republic of China, by NewsRx correspondents, research stated, "Probes for detecting highly reactive oxygen species (hROS) are critical to both understanding the etiology of the disease and optimizing therapeutic interventions. However, problems such as low stability due to autoxidation and photobleaching and unsuitability for biological application in vitro and in vivo, as well as the high cost and complex procedure in synthesis and modification, largely limit their application."
Our news editors obtained a quote from the research from Jilin University, "In this work, binary heterogeneous nanocomplexes (termed as C-dots-AuNC) constructed from gold clusters and carbon dots were reported. The fabrication takes full advantages of the inherent active groups on the surface of the nanoparticles to avoid tedious modification and chemical synthetic processes. Additionally, the assembly endowed C-dots-AuNC with improved performance such as the fluorescence enhancement of AuNCs and stability of C-dots to hROS. Moreover, the dual-emission property allows sensitive imaging and monitoring of the hROS signaling in living cells with high contrast."
According to the news editors, the research concluded: "Importantly, with high physiological stability and excellent biocompatibility, C-dots-AuNC allows for the detection of hROS in the model of local ear inflammation."
For more information on this research see: Heterogeneous Assembled Nanocomplexes for Ratiometric Detection of Highly Reactive Oxygen Species in Vitro and in Vivo. ACS Nano, 2014;8(6):6014-6023. ACS Nano can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; ACS Nano - www.pubs.acs.org/journal/ancac3)
The news editors report that additional information may be obtained by contacting E.G. Ju, Jilin University, Coll Life Sci, Changchun 130012, Jilin, People's Republic of China. Additional authors for this research include Z. Liu, Y.D. Du, Y. Tao, J.S. Ren and X.G. Qu (see also Chalcogens).
Keywords for this news article include: Asia, Changchun, Chalcogens, Oxygen Compounds, Reactive Oxygen Species, People's Republic of China
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