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New Findings on Connective Tissue Cells from King Abdul-Aziz University Summarized (Understanding improved osteoblast behavior on select nanoporous...

August 5, 2014



New Findings on Connective Tissue Cells from King Abdul-Aziz University Summarized (Understanding improved osteoblast behavior on select nanoporous anodic alumina)

By a News Reporter-Staff News Editor at Life Science Weekly -- Research findings on Connective Tissue Cells are discussed in a new report. According to news reporting from Jeddah, Saudi Arabia, by NewsRx journalists, research stated, "The aim of this study was to prepare different sized porous anodic alumina (PAA) and examine preosteoblast (MC3T3-E1) attachment and proliferation on such nanoporous surfaces. In this study, PAA with tunable pore sizes (25 nm, 50 nm, and 75 nm) were fabricated by a two-step anodizing procedure in oxalic acid."

The news correspondents obtained a quote from the research from King Abdul-Aziz University, "The surface morphology and elemental composition of PAA were characterized by field emission scanning electron microscopy and X-ray photoelectron spectroscopy analysis. The nanopore arrays on all of the PAA samples were highly regular. X-ray photoelectron spectroscopy analysis suggested that the chemistry of PAA and flat aluminum surfaces were similar. However, contact angles were significantly greater on all of the PAA compared to flat aluminum substrates, which consequently altered protein adsorption profiles. The attachment and proliferation of preosteoblasts were determined for up to 7 days in culture using field emission scanning electron microscopy and a Cell Counting Kit-8. Results showed that nanoporous surfaces did not enhance initial preosteoblast attachment, whereas preosteoblast proliferation dramatically increased when the PAA pore size was either 50 nm or 75 nm compared to all other samples (P

According to the news reporters, the research concluded: "Thus, this study showed that one can alter surface energy of aluminum by modifying surface nano-roughness alone (and not changing chemistry) through an anodization process to improve osteoblast density, and, thus, should be further studied as a bioactive interface for orthopedic applications."

For more information on this research see: Understanding improved osteoblast behavior on select nanoporous anodic alumina. International Journal of Nanomedicine, 2014;9():3325-3334. International Journal of Nanomedicine can be contacted at: Dove Medical Press Ltd, PO Box 300-008, Albany, Auckland 0752, New Zealand (see also Connective Tissue Cells).

Our news journalists report that additional information may be obtained by contacting S.Y. Ni, King Abdulaziz Univ, Center Excellence Adv Mat Res, Jeddah 21413, Saudi Arabia. Additional authors for this research include C.Y. Li, S.R. Ni, T. Chen and T.J. Webster.

Keywords for this news article include: Asia, Jeddah, Chemicals, Chemistry, Osteoblasts, Saudi Arabia, Connective Tissue Cells

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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