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New Findings on Bone Research Discussed by Researchers at University of Limerick (A bioactive metallurgical grade porous...

August 6, 2014



New Findings on Bone Research Discussed by Researchers at University of Limerick (A bioactive metallurgical grade porous silicon-polytetrafluoroethylene sheet for guided bone regeneration applications)

By a News Reporter-Staff News Editor at Biotech Week -- Researchers detail new data in Bone Research. According to news originating from Limerick, Ireland, by NewsRx correspondents, research stated, "The properties of porous silicon make it a promising material for a host of applications including drug delivery, molecular and cell-based biosensing, and tissue engineering. Porous silicon has previously shown its potential for the controlled release of pharmacological agents and in assisting bone healing."

Our news journalists obtained a quote from the research from the University of Limerick, "Hydroxyapatite, the principle constituent of bone, allows osteointegration in vivo, due to its chemical and physical similarities to bone. Synthetic hydroxyapatite is currently applied as a surface coating to medical devices and prosthetics, encouraging bone in-growth at their surface and improving osseointegration. This paper examines the potential for the use of an economically produced porous silicon particulate-polytetrafluoroethylene sheet for use as a guided bone regeneration device in periodontal and orthopaedic applications. The particulate sheet is comprised of a series of microparticles in a polytetrafluoroethylene matrix and is shown to produce a stable hydroxyapatite on its surface under simulated physiological conditions. The microstructure of the material is examined both before and after simulated body fluid experiments for a period of 1, 7, 14 and 30 days using Scanning Electron Microscopy. The composition is examined using a combination of Energy Dispersive X-ray Spectroscopy, Thin film X-ray diffraction, Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy and the uptake/release of constituents at the fluid-solid interface is explored using Inductively Coupled Plasma-Optical Emission Spectroscopy."

According to the news editors, the research concluded: "Microstructural and compositional analysis reveals progressive growth of crystalline, 'bone-like' apatite on the surface of the material, indicating the likelihood of close bony apposition in vivo."

For more information on this research see: A bioactive metallurgical grade porous silicon-polytetrafluoroethylene sheet for guided bone regeneration applications. Bio-medical Materials and Engineering, 2014;24(3):1563-74 (see also Bone Research).

The news correspondents report that additional information may be obtained from E.G. Chadwick, Materials and Surface Science Institute, University of Limerick, Limerick, Ireland Dept. of Design and Manufacturing Technology, University of Limerick, Limerick, Ireland. Additional authors for this research include O.M. Clarkin, R. Raghavendra and D.A Tanner.

Keywords for this news article include: Tissue Engineering, Europe, Ireland, Limerick, Bone Research, Nanotechnology, Porous Silicon, Emerging Technologies.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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