News Column

New Findings in Enzymes and Coenzymes Described from Biotechnology Center (Post-production modification of industrial enzymes)

August 6, 2014

By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Enzymes and Coenzymes. According to news reporting originating in Delft, Netherlands, by NewsRx journalists, research stated, "Industry has an increasing interest in the use of enzymes as environmentally friendly, highly efficient, and specific bio-catalysts. Enzymes have primarily evolved to function in aqueous environments at ambient temperature and pressure."

The news reporters obtained a quote from the research from Biotechnology Center, "These conditions however do not always correspond with industrial processes or applications, and only a small portion of all known enzymes are therefore suitable for industrial use. Protein engineering can sometimes be applied to convey more desirable properties to enzymes, such as increased stability, but is limited to the 20 naturally occurring amino acids or homologs thereof. Using post-production modification, which has the potential to combine desirable properties from the enzyme and the conjugated compounds, enzymes can be modified with both natural and synthetic molecules. This offers access to a myriad of possibilities for tuning the properties of enzymes. At this moment, however, the effects of post-production modification cannot yet be reliably predicted. The increasing number of applications will improve this so that the potential of this technology can be fully exploited."

According to the news reporters, the research concluded: "This review will focus on post-production modification of enzymes and its use and opportunities in industry."

For more information on this research see: Post-production modification of industrial enzymes. Applied Microbiology and Biotechnology, 2014;98(14):6215-6231. Applied Microbiology and Biotechnology can be contacted at: Springer, 233 Spring St, New York, NY 10013, USA. (Springer -; Applied Microbiology and Biotechnology -

Our news correspondents report that additional information may be obtained by contacting I.J. Minten, DSM Biotechnol Center, NL-2613 AX Delft, Netherlands. Additional authors for this research include N. Abello, M.E.F. Schooneveld-Bergmans and M.A. van den Berg (see also Enzymes and Coenzymes).

Keywords for this news article include: Delft, Europe, Netherlands, Enzymes and Coenzymes

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Biotech Week

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