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New Findings from University of Oulu in the Area of Bacterial Infections Described (Templated in-situ synthesis of gold nanoclusters conjugated to...

August 8, 2014



New Findings from University of Oulu in the Area of Bacterial Infections Described (Templated in-situ synthesis of gold nanoclusters conjugated to drug target bacterial enoyl-ACP reductase, and their application to the detection of mercury ions ...)

By a News Reporter-Staff News Editor at Health & Medicine Week -- New research on Bacterial Infections is the subject of a report. According to news reporting originating in Oulu, Finland, by NewsRx journalists, research stated, "Fluorescent gold nanoclusters (AuNCs) were synthesized using a drug target bacterial enoyl-ACP reductase (FabI) as a template. The physical and chemical properties of the AuNCs were studied by UV-vis absorption, fluorescence, X-ray photoelectron spectroscopy and TEM."

The news reporters obtained a quote from the research from the University of Oulu, "The AuNCs-FabI conjugate was prepared by in situ reduction of tetrachloroaurate in the presence of FabI. The conjugated particles were loaded onto nylon membranes by taking advantage of the electrostatic interaction between the negatively charged AuNCs@FabI and the nylon film which is positively charged at pH 7.4. This results in the formation of a test stripe with sensor spots that can be used to detect Hg(II) ion in the 1 nM to 10 mu M concentration range."

According to the news reporters, the research concluded: "The test stripes are simple, convenient, selective, sensitive, and can be quickly read out with bare eyes after illumination with a UV lamp."

For more information on this research see: Templated in-situ synthesis of gold nanoclusters conjugated to drug target bacterial enoyl-ACP reductase, and their application to the detection of mercury ions using a test stripe. Microchimica Acta, 2014;181(9-10):1029-1034. Microchimica Acta can be contacted at: Springer Wien, Sachsenplatz 4-6, PO Box 89, A-1201 Wien, Austria. (Springer - www.springer.com; Microchimica Acta - www.springerlink.com/content/0026-3672/)

Our news correspondents report that additional information may be obtained by contacting H. Ding, University of Oulu, Bioctr Oulu, Oulu 90014, Finland. Additional authors for this research include H.W. Li, P.C. Liu, J.K. Hiltunen, Y.Q. Wu, Z.J. Chen and J.C. Shen (see also Bacterial Infections).

Keywords for this news article include: Oulu, Europe, Finland, Nanoclusters, Nanotechnology, Emerging Technologies, Bacterial Infections and Mycoses

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Health & Medicine Week


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