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New Data from H. Pahlevaninezhad et al Illuminate Findings in Optical Coherence Tomography (Coregistered autofluorescence-optical coherence...

August 8, 2014

New Data from H. Pahlevaninezhad et al Illuminate Findings in Optical Coherence Tomography (Coregistered autofluorescence-optical coherence tomography imaging of human lung sections)

By a News Reporter-Staff News Editor at Health & Medicine Week -- Researchers detail new data in Optical Coherence Tomography. According to news reporting from Vancouver, Canada, by NewsRx journalists, research stated, "Autofluorescence (AF) imaging can provide valuable information about the structural and metabolic state of tissue that can be useful for elucidating physiological and pathological processes. Optical coherence tomography (OCT) provides high resolution detailed information about tissue morphology."

The news correspondents obtained a quote from the research, "We present coregistered AF-OCT imaging of human lung sections. Adjacent hematoxylin and eosin stained histological sections are used to identify tissue structures observed in the OCT images. Segmentation of these structures in the OCT images allowed determination of relative AF intensities of human lung components. Since the AF imaging was performed on tissue sections perpendicular to the airway axis, the results show the AF signal originating from the airway wall components free from the effects of scattering and absorption by overlying layers as is the case during endoscopic imaging. Cartilage and dense connective tissue (DCT) are found to be the dominant fluorescing components with the average cartilage AF intensity about four times greater than that of DCT."

According to the news reporters, the research concluded: "The epithelium, lamina propria, and loose connective tissue near basement membrane generate an order of magnitude smaller AF signal than the cartilage fluorescence."

For more information on this research see: Coregistered autofluorescence-optical coherence tomography imaging of human lung sections. Journal of Biomedical Optics, 2014;19(3):311-316. Journal of Biomedical Optics can be contacted at: Spie-Soc Photo-Optical Instrumentation Engineers, 1000 20TH St, PO Box 10, Bellingham, WA 98225, USA (see also Optical Coherence Tomography).

Our news journalists report that additional information may be obtained by contacting H. Pahlevaninezhad, BC Canc Res Center, Vancouver, BC V5Z 1L3, Canada. Additional authors for this research include A.M.D. Lee, S. Lam, C. MacAulay and P.M. Lane.

Keywords for this news article include: Canada, Vancouver, British Columbia, Imaging Technology, North and Central America, Optical Coherence Tomography

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Source: Health & Medicine Week

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