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New Cancer Therapy Study Findings Have Been Reported by Researchers at National Institute for Materials Science (Highly Water-Soluble, Porous, and...

August 6, 2014



New Cancer Therapy Study Findings Have Been Reported by Researchers at National Institute for Materials Science (Highly Water-Soluble, Porous, and Biocompatible Boron Nitrides for Anticancer Drug Delivery)

By a News Reporter-Staff News Editor at Biotech Week -- Researchers detail new data in Oncology. According to news reporting originating from Ibaraki, Japan, by NewsRx correspondents, research stated, "Developing materials for 'Nano-vehicles' with clinically approved drugs encapsulated is envisaged to enhance drug therapeutic effects and reduce the adverse effects. However, design and preparation of the biomaterials that are porous, nontoxic, soluble, and stable in physiological solutions and could be easily functionalized for effective drug deliveries are still challenging."

Our news editors obtained a quote from the research from National Institute for Materials Science, "Here, we report an original and simple thermal substitution method to fabricate perfectly water-soluble and porous boron nitride (BN) materials featuring unprecedentedly high hydroxylation degrees. These hydroxylated BNs are biocompatible and can effectively load anticancer drugs (e.g., doxorubicin, DOX) up to contents three times exceeding their own weight."

According to the news editors, the research concluded: "The same or even fewer drugs that are loaded on such BN carriers exhibit much higher potency for reducing the viability of LNCaP cancer cells than free drugs."

For more information on this research see: Highly Water-Soluble, Porous, and Biocompatible Boron Nitrides for Anticancer Drug Delivery. ACS Nano, 2014;8(6):6123-6130. ACS Nano can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; ACS Nano - www.pubs.acs.org/journal/ancac3)

The news editors report that additional information may be obtained by contacting Q.H. Weng, Natl Inst Mat Sci, Nanotechnol Innovat Stn, Tsukuba, Ibaraki 3050047, Japan. Additional authors for this research include B.J. Wang, X.B. Wang, N. Hanagata, X. Li, D.Q. Liu, X. Wang, X.F. Jiang, Y. Bando and D. Golberg (see also Oncology).

Keywords for this news article include: Asia, Japan, Ibaraki, Therapy, Oncology, Chemicals, Chemistry, Boron Nitride, Drug Delivery Systems

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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