The news reporters obtained a quote from the research, "While natural products discovery programs have been gradually abandoned by the big pharma, smaller biotechnology companies and research organizations are taking over the lead in the discovery of novel antibacterials. Recent years have seen new approaches and technologies being developed and integrated in a multidisciplinary effort to further exploit microbial resources and their biosynthetic potential as an untapped source of novel molecules. New strategies to isolate novel species thought to be uncultivable, and synthetic biology approaches ranging from genome mining of microbial strains for cryptic biosynthetic pathways to their heterologous expression have been emerging in combination with high throughput sequencing platforms, integrated bioinformatic analysis, and on-site analytical detection and dereplication tools for novel compounds."
According to the news reporters, the research concluded: "These different innovative approaches are defining a completely new framework that is setting the bases for the future discovery of novel chemical scaffolds that should foster a renewed interest in the identification of novel classes of natural product antibiotics from the microbial world."
For more information on this research see: The re-emerging role of microbial natural products in antibiotic discovery.
Our news correspondents report that additional information may be obtained by contacting O. Genilloud, Fdn MEDINA,
Keywords for this news article include: Antibacterial, Antibiotics, Antimicrobials,
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC
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