News Column

Findings on Molecular Imaging Reported by Investigators at University of Tennessee (Cancer and Comparative Imaging)

August 5, 2014



By a News Reporter-Staff News Editor at Life Science Weekly -- Data detailed on Molecular Imaging have been presented. According to news reporting originating in Knoxville, Tennessee, by NewsRx editors, the research stated, "5 Comparative oncology research is gaining traction as a method for streamlining the drug discovery and development strategies currently in place worldwide. This approach uses the tumor-bearing pet dog as a relevant and complementary model alongside the traditional use of rodents, no-human primates, and other large mammalian species such as purpose-bred dogs or pigs."

The news reporters obtained a quote from the research from the University of Tennessee, "To date, most comparative oncology studies have been designed and executed to evaluate new anticancer drugs using tumor-bearing dogs with specific naturally occurring cancers as models for humans. These studies have proved extremely valuable for modeling pharmacokinetic-pharmacodynamic relationships, refining drug doses and schedules, and validating an individual drug's target in vivo. The National Cancer Institute's Comparative Oncology Trials Consortium () is a cooperative effort that provides infrastructure and resources to support this effort. To complement ongoing efforts in this field, we propose expansion of comparative cancer imaging as a component to drug discovery and development. Diagnostic imaging is critical to diagnosis and management of malignancy in both humans and animals. Molecular imaging techniques allow for detection of disease-specific signals that provide individualized data to aid in patient selection, response to therapy, and prognostication."

According to the news reporters, the research concluded: "In this review, we will highlight the comparative oncology studies that have used molecular imaging techniques, demonstrating the value of spontaneous canine cancers as a research tool in drug and imaging agent development."

For more information on this research see: Cancer and Comparative Imaging. ILAR Journal, 2014;55(1):164-168. ILAR Journal can be contacted at: Oxford Univ Press, Great Clarendon St, Oxford OX2 6DP, England (see also Molecular Imaging).

Our news correspondents report that additional information may be obtained by contacting A.K. LeBlanc, University of Tennessee, Dept. of Radiol, Grad Sch Med, Knoxville, TN 37996, United States.

Keywords for this news article include: Knoxville, Tennessee, United States, Nanotechnology, Molecular Imaging, Emerging Technologies, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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