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Findings from Pamukkale University in the Area of Biosensing Reported (A novel functional conducting polymer as an immobilization platform)

August 6, 2014



By a News Reporter-Staff News Editor at Biotech Week -- Researchers detail new data in Biosensing. According to news reporting originating in Denizli, Turkey, by NewsRx journalists, research stated, "Here, we present the fabrication of conducting polymer based enzymatic and microbial biosensors. To obtain immobilization platforms for both pyranose oxidase (PyOx) and Gluconobacter oxydans, the graphite electrode surface was modified with the polymer of 4-amino-N-(2,5-di(thiophen-2-yl)-1H-pyrrol-1-yl)benzamide (HKCN) which has free amino groups on the surface for further bioconjugation reactions with the biomolecules."

The news reporters obtained a quote from the research from Pamukkale University, "Initially, the electrode surface was covered with HKCN via electropolymerization. Then, either PyOx or G. oxydans cell was stabilized using glutaraldehyde as a cross-linker. After optimization of biosensors, analytical characterization and surface imaging studies were investigated. The change of current depends on glucose concentration between 0.05-1.0 mM and 0.25-2.5 mM with HKCN/PyOx and HKCN/G. oxydans biosensors in batch systems."

According to the news reporters, the research concluded: "Also, the calibration graphs were obtained for glucose in FIA mode, and in this case, linear ranges were found to be 0.01-1.0 mM and 0.1-7.5 mM for HKCN/PyOx and HKCN/G. oxydans, respectively."

For more information on this research see: A novel functional conducting polymer as an immobilization platform. Materials Science & Engineering C-Materials for Biological Applications, 2014;40():148-156. Materials Science & Engineering C-Materials for Biological Applications can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands (see also Biosensing).

Our news correspondents report that additional information may be obtained by contacting E. Guler, Pamukkale University, Fac Art & Sci, Dept. of Chem, Denizli, Turkey. Additional authors for this research include H.C. Soyleyici, D.O. Demirkol, M. Ak and S. Timur.

Keywords for this news article include: Turkey, Denizli, Eurasia, Biosensing, Bioengineering, Bionanotechnology, Nanobiotechnology

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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