Findings from Estacio of Sa University Update Knowledge of Endodontics (Antibacterial, physicochemical and mechanical properties of endodontic sealers containing quaternary ammonium polyethylenimine nanoparticles)
By a News Reporter-Staff News Editor at Health & Medicine Week -- Researchers detail new data in Endodontics. According to news reporting from Rio de Janeiro, Brazil, by NewsRx journalists, research stated, "To evaluate the antibacterial, physicochemical and mechanical properties of two endodontic sealers incorporating quaternary ammonium polyethylenimine (QPEI) nanoparticles at concentrations of 1% and 2% (w/w). The sealers tested were AH Plus and Pulp Canal Sealer EWT in the commercial unmodified form or containing 1% or 2% QPEI."
The news correspondents obtained a quote from the research from the Estacio of Sa University, "Antibacterial activity was evaluated using a direct contact test (DCT) against Enterococcus faecalis ATCC 29212 and two endodontic isolates (RW35 and RN44). Sealers freshly mixed or set for 7 days were exposed to bacterial suspensions for 10, 30 and 60 min. Setting time, flow test, solubility, apparent porosity, dimensional change following setting, wettability, zeta potential and compressive strength were assessed according to the International Standard Organization 6876:2001 (ISO 6876). DCT results revealed that both freshly prepared sealers had antibacterial effects unaffected by QPEI incorporation. Both unmodified sealers had lost much of their antibacterial effects after 7 days. However, for Pulp Canal Sealer EWT incorporated with 1% and 2% QPEI nanoparticles, the antibacterial effects against all test E. faecalis strains within 30 and 60 min of contact were significantly greater than the unmodified formula. Addition of QPEI resulted in no significant increase in the antibacterial effects of AH Plus after ageing. As for physicochemical and mechanical tests, setting time, wettability and zeta potential were influenced by the presence of QPEI nanoparticles."
According to the news reporters, the research concluded: "Incorporation of QPEI nanoparticles can improve the long-term antibacterial activity of Pulp Canal Sealer EWT without relevant changes in physicochemical and mechanical properties."
For more information on this research see: Antibacterial, physicochemical and mechanical properties of endodontic sealers containing quaternary ammonium polyethylenimine nanoparticles. International Endodontic Journal, 2014;47(8):725-734. International Endodontic Journal can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - www.wiley.com/; International Endodontic Journal - onlinelibrary.wiley.com/journal/10.1111/(ISSN)1365-2591)
Our news journalists report that additional information may be obtained by contacting J. Barros, Estacio de Sa Univ, Fac Dental, Dept. of Endodont, Rio De Janeiro, RJ, Brazil. Additional authors for this research include M.G. Silva, M.A. Rodrigues, F.R.F. Alves, M.A. Lopes, I. Pina-Vaz and J.F. Siqueira (see also Endodontics).
Keywords for this news article include: Brazil, Chemicals, Chemistry, Endodontics, Nanoparticle, South America, Rio de Janeiro, Nanotechnology, Quaternary Ammonium, Emerging Technologies
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