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Data on Globins Discussed by Researchers at Department of Biomedical Sciences (Feasibility of interstitial near-infrared radiance spectroscopy...

August 8, 2014



Data on Globins Discussed by Researchers at Department of Biomedical Sciences (Feasibility of interstitial near-infrared radiance spectroscopy platform for ex vivo canine prostate studies: optical properties extraction, hemoglobin and water ...)

By a News Reporter-Staff News Editor at Health & Medicine Week -- A new study on Proteins is now available. According to news originating from Charlottetown, Canada, by NewsRx correspondents, research stated, "The canine prostate is a close match for the human prostate and is used in research of prostate cancers. Determining accurately optical absorption and scattering properties of the gland in a wide spectral range (preferably in a minimally invasive way), linking optical properties to concentrations of major endogenous chromophores, and detecting the presence of localized optical inhomogeneities like inclusions of gold nanoparticles for therapeutic and diagnostic purposes, are among the major challenges for researchers."

Our news journalists obtained a quote from the research from the Department of Biomedical Sciences, "The goal of the article is to demonstrate a feasibility of the multifunctional radiance spectroscopy platform in providing the required information. For ex vivo canine prostate, extraction of the effective attenuation and diffusion coefficients using relative cw radiance measurements was demonstrated in the 650- to 900-nm range. The derived absorption coefficient was decomposed to contributions from 9.0 mu M HbO(2), 29.6 mu M Hb, and 0.47 fractional volume of H2O. Detection of a localized inclusion containing similar to 1.5. 10(10) gold nanorods (0.8 mu g Au) at 10 mm distance from the urethra was achieved with the detector in the urethra and the light source in a virtual rectum position."

According to the news editors, the research concluded: "The platform offers the framework for a systematic study of various chromophores in the prostate that can be used as comprehensive diagnostic markers."

For more information on this research see: Feasibility of interstitial near-infrared radiance spectroscopy platform for ex vivo canine prostate studies: optical properties extraction, hemoglobin and water concentration, and gold nanoparticles detection. Journal of Biomedical Optics, 2014;19(5):294-304. Journal of Biomedical Optics can be contacted at: Spie-Soc Photo-Optical Instrumentation Engineers, 1000 20TH St, PO Box 10, Bellingham, WA 98225, USA (see also Proteins).

The news correspondents report that additional information may be obtained from S. Grabtchak, Atlantic Vet College, Dept. of Biomed Sci, Charlottetown, PE C1A 4P3, Canada. Additional authors for this research include L.G. Montgomery and W.M. Whelan.

Keywords for this news article include: Canada, Hemoglobins, Charlottetown, Blood Proteins, Nanotechnology, Gold Nanoparticles, Prince Edward Island, Emerging Technologies, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Health & Medicine Week


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