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NeuroPace RNS System to Figure Heavily in DARPA's Restoring Active Memory Program

July 30, 2014

NeuroPace detailed its partnership with the Defense Advanced Research Projects Agency (DARPA) Restoring Active Memory (RAM) teams at the University of Pennsylvania and the University of California, Los Angeles (UCLA) to develop new treatments for memory deficits using neurostimulation.

According to a media release, the RNS System is the world's only commercially available implantable closed-loop responsive neurostimulator system. NeuroPace received premarket approval (PMA) from the U.S. Food and Drug Administration (FDA) for the RNS System in November 2013. It is approved as a treatment for adults with partial onset seizures with one or two seizure onset zones whose seizures have not been controlled with two or more antiepileptic drugs.

"Using the RNS System, we will be able to immediately explore ways in which brain stimulation can restore memory function in patients with epilepsy. Insights derived from these early studies will help to guide future research in patients with other neurological disorders that result in memory loss," said Michael Kahana, PhD, principal investigator at the University of Pennsylvania.

"The RNS System is the only commercially available product that continuously monitors the brain's electrical signals, delivers stimulation only when needed and then monitors the response," said Frank Fischer, CEO at NeuroPace. "This capability is critical to the research phase of projects like the DARPA RAM program. Restoring active memory could improve the lives of so many. We are thrilled to be a part of this program and hope to be part of similar brain research and product development projects in the future."

NeuroPace designs, develops, manufactures and markets implantable devices for the treatment of neurological disorders.

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