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Researchers from Catalan Institution for Research and Advanced Studies (ICREA) Provide Details of New Studies and Findings in the Area of Microscopy...

August 1, 2014



Researchers from Catalan Institution for Research and Advanced Studies (ICREA) Provide Details of New Studies and Findings in the Area of Microscopy (Nanophotonic Approaches for Nanoscale Imaging and Single-Molecule Detection at Ultrahigh ...)

By a News Reporter-Staff News Editor at Science Letter -- Fresh data on Microscopy are presented in a new report. According to news reporting originating from Barcelona, Spain, by NewsRx correspondents, research stated, "Over the last decade, we have witnessed an outburst of many different optical techniques aimed at breaking the diffraction limit of light, providing super-resolution imaging on intact fixed cells. In parallel, single-molecule detection by means of fluorescence has become a common tool to investigate biological interactions at the molecular level both in vitro and in living cells."

Our news editors obtained a quote from the research from Catalan Institution for Research and Advanced Studies (ICREA), "Despite these advances, visualization of dynamic events at relevant physiological concentrations at the nanometer scale remains challenging. In this review, we focus on recent advancements in the field of nanophotonics toward nanoimaging and single-molecule detection at ultrahigh sample concentrations. These approaches rely on the use of metal nanostructures known as optical antennas to localize and manipulate optical fields at the nanometer scale. We highlight examples on how different optical antenna geometries are being implemented for nanoscale imaging of cell membrane components."

According to the news editors, the research concluded: "We also discuss different implementations of selfstanding and two-dimensional antenna arrays for studying nanoscale dynamics in living cell membranes as well as detection of individual biomolecular interactions in the mu M range for sensing applications."

For more information on this research see: Nanophotonic Approaches for Nanoscale Imaging and Single-Molecule Detection at Ultrahigh Concentrations. Microscopy Research and Technique, 2014;77(7):537-545. Microscopy Research and Technique can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - www.wiley.com/; Microscopy Research and Technique - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1097-0029)

The news editors report that additional information may be obtained by contacting M. Mivelle, ICREA, Barcelona 08010, Spain. Additional authors for this research include T.S. Van Zanten, C. Manzo and M.F. Garcia-Parajo (see also Microscopy).

Keywords for this news article include: Barcelona, Spain, Europe, Microscopy

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Science Letter


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