News Column

Studies from K. Kotani and Co-Researchers in the Area of Blood Cells Reported (Development of a new point-of-care testing system for measuring white...

July 28, 2014



Studies from K. Kotani and Co-Researchers in the Area of Blood Cells Reported (Development of a new point-of-care testing system for measuring white blood cell and C-reactive protein levels in whole blood samples)

By a News Reporter-Staff News Editor at Proteomics Weekly -- Investigators publish new report on Blood Cells. According to news originating from Tochigi, Japan, by NewsRx correspondents, research stated, "White blood cell (WBC) count and C-reactive protein (CRP) level are the most common markers of inflammation. There is a growing need for point-of-care testing (POCT) of WBC and CRP, and more advances in convenient devices are required."

Our news journalists obtained a quote from the research, "We developed an analyzer-free POCT system for measuring WBC and CRP using a low volume blood sample. The POCT-WBC is based on the granulocyte esterase assay, while the POCT-CRP is based on the immunochromatographic assay. These kits were examined for precision as well as correlation with currently used popular commercial automated assays. The correlations were clinically analyzed in children with acute infection (n = 62; mean age 4.2 y). The correlations regarding the monitoring of values were further examined in several follow-up subjects. The POCT-WBC and POCT-CRP kits demonstrated good precision. POCT-WBC exhibited a significantly close correlation with those of the control assay (r = 0.94, p< 0.05). The results of POCT-CRP also exhibited a significantly close correlation with those of the control assay (r = 0.94, p< 0.05). In the follow-up study, the results of the respective kits were similar to those of the control assays."

According to the news editors, the research concluded: "The POCT-WBC and POCT-CRP are promising tools for assessing infection in clinical practice."

For more information on this research see: Development of a new point-of-care testing system for measuring white blood cell and C-reactive protein levels in whole blood samples. Clinica Chimica Acta, 2014;433():145-149. Clinica Chimica Acta can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Clinica Chimica Acta - www.elsevier.com/wps/product/cws_home/506018)

The news correspondents report that additional information may be obtained from K. Kotani, Eiken Chem Co Ltd, Shimotsuga, Tochigi 3290114, Japan. Additional authors for this research include T. Minami, T. Abe, J. Sato, N. Taniguchi and T. Yamada (see also Blood Cells).

Keywords for this news article include: Tochigi, Japan, Asia, Acute-Phase Proteins, Albumins, Blood Cells, C Reactive Protein, C-Reactive Protein, Immunology, Immunoproteins, Proteomics

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


For more stories covering the world of technology, please see HispanicBusiness' Tech Channel



Source: Proteomics Weekly


Story Tools






HispanicBusiness.com Facebook Linkedin Twitter RSS Feed Email Alerts & Newsletters