Studies from Indian Institute of Technology Yield New Information about Urea (SnO2 Quantum Dots-Reduced Graphene Oxide Composite for Enzyme-Free Ultrasensitive Electrochemical Detection of Urea)
By a News Reporter-Staff News Editor at Biotech Week -- Current study results on Urea have been published. According to news reporting originating from Maharashtra, India, by NewsRx correspondents, research stated, "Most of the urea sensors are biosensors and utilize urease, which limit their use in harsh environments. Recently, because of their exceptional ability to endorse faster electron transfer, carbonaceous material composites and quantum dots are being used for fabrication of a sensitive transducer surface for urea biosensors."
Our news editors obtained a quote from the research from the Indian Institute of Technology, "We demonstrate an enzyme free ultrasensitive urea sensor fabricated using a SnO2 quantum dots (QDs)/reduced graphene oxide (RGO) composite. Due to the synergistic effect of the constituents, the SnO2 QDs/RGO (SRGO) composite proved to be an excellent probe for electrochemical sensing. The morphology and structure of the composite was characterized by various techniques, and it was observed that SnO2 QDs are decorated on RGO layers. Electrochemical studies were performed to evaluate the characteristics of the sensor toward detection of urea. Amperometry studies show that the SRGO/GCE electrode is sensitive to urea in the concentration range of 1.6 x 10(-14)-3.9 x 10(-12) M, with a detection limit of as low as 11.7 fM. However, this is an indirect measurement for urea wherein the analytical signal is recorded as a decrease in the amperommetric and/or voltammetric current from the solution redox species ferrocyanide. The porous structure of the SRGO matrix offers a very low transport barrier and thus promotes rapid diffusion of the ionic species from the solution to the electrode, leading to a rapid response time (similar to 5 s) and ultrahigh sensitivity (1.38 mu A/fM)."
According to the news editors, the research concluded: "Good analytical performance in the presence of interfering agents, low cost, and easy synthesis methodology suggest that SRGO can be quite promising as an electroactive material for effective urea sensing."
For more information on this research see: SnO2 Quantum Dots-Reduced Graphene Oxide Composite for Enzyme-Free Ultrasensitive Electrochemical Detection of Urea. Analytical Chemistry, 2014;86(12):5914-5921. Analytical Chemistry can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Analytical Chemistry - www.pubs.acs.org/journal/ancham)
The news editors report that additional information may be obtained by contacting D. Dutta, Indian Inst Technol, Dept. of Met Engn & Mat Sci, IITB Monash Res Academy, Bombay 400076, Maharashtra, India. Additional authors for this research include S. Chandra, A.K. Swain and D. Bahadur (see also Urea).
Keywords for this news article include: Maharashtra, India, Asia, Bioengineering, Bionanotechnology, Biosensing, Biotechnology, Chemistry, Electrochemical, Emerging Technologies, Enzymes and Coenzymes, Nanobiotechnology, Nanotechnology, Organic Chemicals, Quantum Dots, Quantum Physics, Urea
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