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Researchers from Trudeau Institute Report New Studies and Findings in the Area of Immunology (Invariant NKT cells provide innate and adaptive help...

July 30, 2014



Researchers from Trudeau Institute Report New Studies and Findings in the Area of Immunology (Invariant NKT cells provide innate and adaptive help for B cells)

By a News Reporter-Staff News Editor at Vaccine Weekly -- Current study results on Immunology have been published. According to news reporting from Saranac Lake, New York, by NewsRx journalists, research stated, "B cells rely on CD4(+) T cells helper signals to optimize their responses to T-dependent antigens."

The news correspondents obtained a quote from the research from Trudeau Institute, "Recently another subset of T cells has been identified which provides help for B cells, invariant natural killer T (iNKT) cells. iNKT cells are, unique because they provide both innate and adaptive forms of help to B cells, with divergent outcomes. iNKT cells are widely distributed throughout the spleen at rest, consolidate in the marginal zone of the spleen early after activation, and are later found in germinal centers."

According to the news reporters, the research concluded: "Understanding the activation requirements for iNKT cells has led to the development of glycolipid containing nanoparticles which efficiently activate iNKT cells, enhance their cooperation with B cells, and which hold promise for vaccine development."

For more information on this research see: Invariant NKT cells provide innate and adaptive help for B cells. Current Opinion in Immunology, 2014;28():12-17. Current Opinion in Immunology can be contacted at: Current Biology Ltd, 84 Theobalds Rd, London WC1X 8RR, England. (Elsevier - www.elsevier.com; Current Opinion in Immunology - www.elsevier.com/wps/product/cws_home/601305)

Our news journalists report that additional information may be obtained by contacting E.E. Vomhof-DeKrey, Trudeau Inst, Saranac Lake, NY 12983, United States. Additional authors for this research include J. Yates and E.A. Leadbetter (see also Immunology).

Keywords for this news article include: Saranac Lake, New York, United States, North and Central America, Immunology

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Vaccine Weekly


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