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Recent Research from Graduate School of Engineering Highlight Findings in Tissue Engineering (ToF-SIMS evaluation of calcium-containing...

July 30, 2014



Recent Research from Graduate School of Engineering Highlight Findings in Tissue Engineering (ToF-SIMS evaluation of calcium-containing silica/gamma-PGA hybrid systems for bone regeneration)

By a News Reporter-Staff News Editor at Biotech Week -- Investigators discuss new findings in Biomedicine and Biomedical Engineering. According to news reporting originating in Nagoya, Japan, by NewsRx journalists, research stated, "Inorganic/organic hybrids have great potential for the production of bioactive scaffolds which have tailored mechanical properties and degradation rates suitable for tissue engineering. For bone regeneration, calcium incorporation into hybrids at low temperatures is important due to its ability to stimulate new bone formation."

The news reporters obtained a quote from the research from the Graduate School of Engineering, "As a consequence, understanding the homogeneity of the critical inorganic and organic components will be the key to the development of such hybrids. The aim of this interdisciplinary study was to use time-of-flight secondary ion mass spectrometry (ToF-SIMS) to determine the homogeneity of these critical components. We evaluated various sal-gel silica/gamma-polyglutamic acid (gamma-PGA) hybrid systems produced using different routes to introduce the calcium, thereby tailoring and optimizing hybrid syntheses and processing routes. Dimethyl carbonate (DMC) was used to improve the inorganic/organic coupling and its influence on the homogeneity of the hybrid structures was also examined. The results revealed that the calcium salt form of gamma-PGA was promising for calcium incorporation since homogeneous products could be obtained."

According to the news reporters, the research concluded: "The ToF-SIMS data also indicated that the reaction time of hybrid synthesis and the timing of the addition of DMC can affect the homogeneity of hybrids."

For more information on this research see: ToF-SIMS evaluation of calcium-containing silica/gamma-PGA hybrid systems for bone regeneration. Applied Surface Science, 2014;309():231-239. Applied Surface Science can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Applied Surface Science - www.elsevier.com/wps/product/cws_home/505669)

Our news correspondents report that additional information may be obtained by contacting D. Wang, Nagoya Inst Technol, Grad Sch Engn, Dept. of Frontier Mat, Showa Ku, Nagoya, Aichi 4668555, Japan. Additional authors for this research include J. Nakamura, G. Poologasundarampillai, T. Kasuga, J.R. Jones and D.S. McPhail (see also Biomedicine and Biomedical Engineering).

Keywords for this news article include: Nagoya, Japan, Asia, Bioengineering, Biomedical Engineering, Biomedicine, Biomedicine and Biomedical Engineering, Bone Regeneration, Bone Research, Regeneration Medicine, Tissue Engineering

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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