New Supramolecular Research Study Findings Have Been Reported by Researchers at University of Paris (Supramolecular Control of Biomimetic Coordination - Zn-II Cavity Complexes Presenting Two Differentiated Labile Sites in cis Positions)
By a News Reporter-Staff News Editor at Biotech Week -- Research findings on Supramolecular Research are discussed in a new report. According to news reporting out of Paris, France, by NewsRx editors, research stated, "A supramolecular approach to model the active sites of metalloenzymes is to associate a cavity with a tripodal coordination core. One key feature of many enzymes is the possible binding of two different ligands in cis positions relative to each other, which has not yet been described for cavity complexes."
Our news journalists obtained a quote from the research from the University of Paris, "Here, the bowl shape of resorcinarene allows such a coordination environment for ZnII complexes. A detailed NMR study with various carboxylic acids evidences size-, shape-, and, thus, regioselectivity for carboxylate coordination in the endo position, the exo position, or both. The coordination of diketonates unambiguously demonstrates the relative cis position of the two labile sites present in the tris(imidazole)zinc(II) bowl complex. An interesting intramolecular exchange process was also observed."
According to the news editors, the research concluded: "Finally, a comparison with calixarene-based complexes (so-called funnel complexes) further highlights the key role of the cavity in the control of properties of the metal ion."
For more information on this research see: Supramolecular Control of Biomimetic Coordination - Zn-II Cavity Complexes Presenting Two Differentiated Labile Sites in cis Positions. European Journal of Inorganic Chemistry, 2014;2014(17):2819-2828. European Journal of Inorganic Chemistry can be contacted at: Wiley-V C H Verlag Gmbh, Boschstrasse 12, D-69469 Weinheim, Germany. (Wiley-Blackwell - www.wiley.com/; European Journal of Inorganic Chemistry - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1099-0682c)
Our news journalists report that additional information may be obtained by contacting J. Gout, University of Paris, Lab Chim & Biochim Pharmacol & Toxicol, CNRS, UMR 8601, F-75006 Paris, France. Additional authors for this research include S. Rat, O. Bistri and O. Reinaud (see also Supramolecular Research).
Keywords for this news article include: Paris, France, Europe, Bioengineering, Biomimetics, Bionanotechnology, Biotechnology, Emerging Technologies, Nanobiotechnology, Nanotechnology, Supramolecular, Supramolecular Research
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC