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New Inflammation Findings from D.L. Bunzen and Co-Researchers Reported (Middle ear packing materials: comparison between absorbable hemostatic...

August 1, 2014



New Inflammation Findings from D.L. Bunzen and Co-Researchers Reported (Middle ear packing materials: comparison between absorbable hemostatic gelatine sponge and sugarcane biopolymer sponge in rats)

By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators publish new report on Inflammation. According to news reporting out of Recife, Brazil, by NewsRx editors, research stated, "Several biomaterials can be used in ear surgery to pack the middle ear or support the graft. The absorbable gelatin sponge is the most widely used, but it may produce fibrosis and impair ventilation of the middle ear."

Our news journalists obtained a quote from the research, "This experimental study aimed to investigate the inflammatory effects of the sugarcane biopolymer sponge (BP) in the rat middle ear compared with absorbable gelatin sponge (AGS). Prospective experimental study design. Thirty adult female Wistar rats were allocated to receive the BP sponge into the right ear and AGS into the left ear. Animals were randomly killed at 4 and 12 weeks post-procedure. Qualitative histological assessments were performed to evaluate the inflammatory reaction in the tympanic bullae. The BP sponge caused inflammation more intense and persistent than AGS. The BP was not absorbed during the experiment. Fibrosis was observed only in the ears with AGS. There were thickening of the mucosa and neoangiogenesis in the group of AGS. Despite inflammation, the BP sponge produced less fibrosis and neoangiogenesis compared to AGS."

According to the news editors, the research concluded: "The sponge BP appeared to be a non-absorbable biomaterial in the middle ear."

For more information on this research see: Middle ear packing materials: comparison between absorbable hemostatic gelatine sponge and sugarcane biopolymer sponge in rats. Brazilian Journal of Otorhinolaryngology, 2014;80(3):237-244. Brazilian Journal of Otorhinolaryngology can be contacted at: Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, Av Indianopolos 740, Moema, Sao Paulo, Sp 04062-001, Brazil (see also Inflammation).

Our news journalists report that additional information may be obtained by contacting D.L. Bunzen, Univ Fed Pernambuco UFPE??Dept. of Pathol, Recife, PE, Brazil. Additional authors for this research include N. Lins, M.D. Leal, M.M.D. Lira and S.D.C. Neto.

Keywords for this news article include: Recife, Brazil, South America, Inflammation

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Health & Medicine Week


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