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Findings from Max-Planck-Institute for Colloids and Interfaces Yields New Data on Chirality (Helfrich's concept of intrinsic force and its molecular...

July 30, 2014



Findings from Max-Planck-Institute for Colloids and Interfaces Yields New Data on Chirality (Helfrich's concept of intrinsic force and its molecular origin in bilayers and monolayers)

By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Chirality. According to news originating from Potsdam, Germany, by NewsRx correspondents, research stated, "Bilayers and monolayers are excellent models of biological membranes. The constituents of the biological membranes such as lipids, cholesterols and proteins are chiral."

Our news journalists obtained a quote from the research from Max-Planck-Institute for Colloids and Interfaces, "Chiral molecules are abundant in nature (protein, nucleic add and lipid). It is obvious that relationship between chirality and morphology (as well as function) of biological membrane is of interest for its fundamental importance and has technological implication regarding various membrane functions. The recent years have witnessed that a number of experimental studies in biomimetic systems have shown fascinating morphologies where chirality of the constituent molecule has derisive influence. Significant progress is made towards the understanding of these systems from the theoretical and computational studies. Helfrich's concept of intrinsic force arising from chirality is a milestone in understanding the biomimetic system such as bilayer and the related concepts, further progresses in molecular understanding made in recent years and experimental studies revealing the influence of chirality on morphology are the focus of the present review. Helfrich's concept of intrinsic force arising due to chirality is useful in understanding two-dimensional bilayers and one-dimensional monolayers and related mimetic systems. Various experimental techniques are used, which can probe the molecular architecture of these mimetic systems at different length scales and both macroscopic (thermodynamic) as well as microscopic (molecular) theories are developed. These studies are aimed to understand the role of chirality in the molecular interaction when the corresponding molecule is present in an aggregate. When one looks into the variety of morphologies exhibited by three-dimensional bilayer and two-dimensional monolayer, the later types of systems are more exotic in the sense that they show more diversity and interesting chiral discrimination. Helfrich's concept of intrinsic force may be considered useful in both cases. The intrinsic force due to chirality is the decisive factor in determining morphology which is explained by molecular approaches."

According to the news editors, the research concluded: "Finally, biological and technological implications of such morphological variations are briefly mentioned."

For more information on this research see: Helfrich's concept of intrinsic force and its molecular origin in bilayers and monolayers. Advances in Colloid and Interface Science, 2014;208():110-120. Advances in Colloid and Interface Science can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Advances in Colloid and Interface Science - www.elsevier.com/wps/product/cws_home/500842)

The news correspondents report that additional information may be obtained from N. Nandi, Max Planck Inst Colloids & Interfaces, D-14424 Potsdam, Germany (see also Chirality).

Keywords for this news article include: Potsdam, Germany, Europe, Bioengineering, Biomimetics, Bionanotechnology, Biotechnology, Chirality, Emerging Technologies, Nanobiotechnology, Nanotechnology

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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