Department of Civil & Environmental Engineering Reports Findings in Biomedicine and Biomedical Engineering (Fatigue behaviour of Nitinol peripheral stents: The role of plaque shape studied with computational structural analyses)
By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Biotechnology. According to news reporting originating in Milan, Italy, by NewsRx journalists, research stated, "Fatigue resistance of Nitinol stents implanted into femoro-popliteal arteries is a critical issue for the particular biomechanical environment of this district. Hip and knee joint movements due to the cyclic daily activity expose the superficial femoral artery (SFA), and therefore the implanted stents, to quite large and cyclic deformations influencing stent fatigue resistance."
The news reporters obtained a quote from the research from the Department of Civil & Environmental Engineering, "Objective of this work is to provide a tool based on finite element analysis able to evaluate the biomechanical effect of SFA on stent fatigue resistance. Computer simulations of the treatment of stenotic vessel by angioplasty and stenting and of the subsequent in vivo loading conditions (axial compression and bending) were carried out. Three different stenotic vessel models were defined, by keeping a constant stenosis rate and changing the plaque sharpness and number of stenoses. The fatigue behaviour was analysed comparing the amplitude and mean value distribution of the first principal strain in the whole stent for the different simulated conditions. Results showed that the maximum mean strain is similar in all the models, while the alternating strain is related to both plaque shape and loading conditions."
According to the news reporters, the research concluded: "This study confirms the requisite of replicating in vivo loading conditions. It also reveals the importance of taking into account the thickness variation of the vessel in the stenotic zone in the assessment of the stent fatigue resistance."
For more information on this research see: Fatigue behaviour of Nitinol peripheral stents: The role of plaque shape studied with computational structural analyses. Medical Engineering & Physics, 2014;36(7):842-849. Medical Engineering & Physics can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Medical Engineering & Physics - www.elsevier.com/wps/product/cws_home/30456)
Our news correspondents report that additional information may be obtained by contacting E. Dordoni, Politecn Milan, Dept. of Civil & Environm Engn, I-20133 Milan, Italy. Additional authors for this research include A. Meoli, W. Wu, G. Dubini, F. Migliavacca, G. Pennati and L. Petrini (see also Biotechnology).
Keywords for this news article include: Milan, Italy, Europe, Biotechnology
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