News Column

Data on Engineering Reported by Researchers at Open University (Engineered neural tissue for peripheral nerve repair)

July 29, 2014



By a News Reporter-Staff News Editor at Life Science Weekly -- Data detailed on Engineering have been presented. According to news originating from Milton Keynes, United Kingdom, by NewsRx correspondents, research stated, "A new combination of tissue engineering techniques provides a simple and effective method for building aligned cellular biomaterials. Self-alignment of Schwann cells within a tethered type-1 collagen matrix, followed by removal of interstitial fluid produces a stable tissue-like biomaterial that recreates the aligned cellular and extracellular matrix architecture associated with nerve grafts."

Our news journalists obtained a quote from the research from Open University, "Sheets of this engineered neural tissue supported and directed neuronal growth in a co-culture model, and initial in vivo tests showed that a device containing rods of rolled-up sheets could support neuronal growth during rat sciatic nerve repair (5 mm gap). Further testing of this device for repair of a critical-sized 15 mm gap showed that, at 8 weeks, engineered neural tissue had supported robust neuronal regeneration across the gap."

According to the news editors, the research concluded: "This is, therefore, a useful new approach for generating anisotropic engineered tissues, and it can be used with Schwann cells to fabricate artificial neural tissue for peripheral nerve repair."

For more information on this research see: Engineered neural tissue for peripheral nerve repair. Biomaterials, 2013;34(30):7335-43. (Elsevier - www.elsevier.com; Biomaterials - www.elsevier.com/wps/product/cws_home/30392)

The news correspondents report that additional information may be obtained from M. Georgiou, The Open University, Walton Hall, Milton Keynes, UK. Additional authors for this research include S.C. Bunting, H.A. Davies, A.J. Loughlin, J.P. Golding and J.B Phillips (see also Engineering).

Keywords for this news article include: Milton Keynes, United Kingdom, Europe, Engineering.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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